Literature DB >> 10933190

Immunotherapy of hematologic malignancies and metastatic solid tumors in experimental animals and man.

S Slavin1, R Or, T Prighozina, O Gurevitch, M Aker, S Panighari, M Shapira, A Nagler.   

Abstract

Following engraftment of donor hematopoietic cells and induction of host-versus-graft tolerance, immunocompetent lymphocytes of donor origin can induce graft-versus-leukemia (GVL) and graft-versus-tumor (GVT) effects. Engraftment of allogeneic bone marrow cells can be accomplished following non-myeloablative conditioning while possibly controlling graft-versus-host disease (GVHD). GVL and GVT effects may thus be successfully accomplished following non-myeloablative stem cell transplantation (NST) as shown by data derived from experimental animals and man.

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Year:  2000        PMID： 10933190     DOI： 10.1038/sj.bmt.1702356

Source DB:  PubMed          Journal:  Bone Marrow Transplant        ISSN： 0268-3369            Impact factor:   5.483


  4 in total

1.  Site-specific mutations in the mature form of human IL-18 with enhanced biological activity and decreased neutralization by IL-18 binding protein.

Authors:  S H Kim; T Azam; D Y Yoon; L L Reznikov; D Novick; M Rubinstein; C A Dinarello
Journal:  Proc Natl Acad Sci U S A       Date:  2001-03-13       Impact factor: 11.205

2.  Nonmyeloablative stem cell transplantation as immunotherapy for kidney cancer and other metastatic solid tumors.

Authors:  Cristian Carvallo; Richard Childs
Journal:  Cytotechnology       Date:  2003-03       Impact factor: 2.058

3.  Immunomodulation with dendritic cells and donor lymphocyte infusion converge to induce graft vs neuroblastoma reactions without GVHD after allogeneic bone marrow transplantation.

Authors:  S Ash; J Stein; N Askenasy; I Yaniv
Journal:  Br J Cancer       Date:  2010-10-26       Impact factor: 7.640

4.  Combination of anti-CD4 antibody treatment and donor lymphocyte infusion ameliorates graft-versus-host disease while preserving graft-versus-tumor effects in murine allogeneic hematopoietic stem cell transplantation.

Authors:  Satoshi Ueha; Shoji Yokochi; Yoshiro Ishiwata; Mizuha Kosugi-Kanaya; Yusuke Shono; Shiro Shibayama; Satoru Ito; Kouji Matsushima
Journal:  Cancer Sci       Date:  2017-08-29       Impact factor: 6.716
  4 in total

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