Literature DB >> 10932966

Management of undescended testis.

U A Khatwa1, P S Menon.   

Abstract

The term cryptorchidism indicates a testis, which has failed to descend to the scrotum and is located at any point along the normal path of descent or at an ectopic site. Hormones play a pivotal role in testicular descent except during the migration to the level of internal inguinal ring. Cryptorchidism is present in about 4.5% of newborns with a higher incidence in preterms. The incidence decreases to 1.2% by the first year. It is classified as palpable and impalpable. The most common site of an ectopic testis is superficial inguinal pouch. Retractile testis is often bilateral and most common in boys between 5 and 6 years of age. Hypospadias and inguinal hernias are the most common associated anomalies seen with undescended testis. A thorough clinical examination helps in arriving at the etiology. A short hCG stimulation test helps to exclude anorchia. Different imaging techniques are of little help in diagnosis and require the help of an experienced radiologist. Laparoscopy has an important role in the diagnosis and management of undescended testis. The common complications include torsion and atrophy of testis. Infertility is seen in about 40% of unilateral and 70% of bilateral cryptorchidism. Undescended testis is 20 to 40 times more likely to undergo malignant transformation than normal testis. Both hCG and GnRH have been used with limited success in these children. All boys with cryptorchidism should be referred to a pediatric surgeon before 2 years of age. These children should be followed up every year after surgery to identify testicular tumors.

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Year:  2000        PMID: 10932966     DOI: 10.1007/bf02859466

Source DB:  PubMed          Journal:  Indian J Pediatr        ISSN: 0019-5456            Impact factor:   1.967


  27 in total

1.  Management of the impalpable testis: the role of laparoscopy.

Authors:  C T Baillie; G Fearns; L Kitteringham; R R Turnock
Journal:  Arch Dis Child       Date:  1998-11       Impact factor: 3.791

2.  Hormonal therapy of cryptorchidism with human chorionic gonadotropin(HCG).

Authors:  J C Job; P Canlorbe; J M Garagorri; J E Toublanc
Journal:  Urol Clin North Am       Date:  1982-10       Impact factor: 2.241

Review 3.  Embryological controversies in testicular descent.

Authors:  J M Hutson; S W Beasley
Journal:  Semin Urol       Date:  1988-05

4.  Paternity after unilateral cryptorchidism: a controlled study.

Authors:  P A Lee; L A O'Leary; N J Songer; M T Coughlin; M F Bellinger; R E LaPorte
Journal:  Pediatrics       Date:  1996-10       Impact factor: 7.124

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Authors:  R Rabinowitz; W C Hulbert
Journal:  Pediatr Rev       Date:  1994-07

6.  Hormonal therapy of cryptorchidism. A randomized, double-blind study comparing human chorionic gonadotropin and gonadotropin-releasing hormone.

Authors:  J Rajfer; D J Handelsman; R S Swerdloff; R Hurwitz; H Kaplan; T Vandergast; R M Ehrlich
Journal:  N Engl J Med       Date:  1986-02-20       Impact factor: 91.245

7.  Prevalence and natural history of cryptorchidism.

Authors:  G S Berkowitz; R H Lapinski; S E Dolgin; J G Gazella; C A Bodian; I R Holzman
Journal:  Pediatrics       Date:  1993-07       Impact factor: 7.124

8.  Cryptorchidism: a prospective study of 7500 consecutive male births, 1984-8. John Radcliffe Hospital Cryptorchidism Study Group.

Authors: 
Journal:  Arch Dis Child       Date:  1992-07       Impact factor: 3.791

9.  Spermatic venography in undescended testes.

Authors:  T Riebel; D Gonnermann; R P Willig
Journal:  Pediatr Radiol       Date:  1987

Review 10.  Cryptorchidism: isolated and associated with other genitourinary defects.

Authors:  J S Elder
Journal:  Pediatr Clin North Am       Date:  1987-08       Impact factor: 3.278

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  4 in total

1.  Testicular torsion in the inguinal region in an extremely low birth weight infant.

Authors:  Yu Jin Jung; Jae Min Chung
Journal:  Korean J Pediatr       Date:  2010-09-13

Review 2.  Epidemiology, classification and management of undescended testes: does medication have value in its treatment?

Authors:  Ayhan Abacı; Gönül Çatlı; Ahmet Anık; Ece Böber
Journal:  J Clin Res Pediatr Endocrinol       Date:  2013

Review 3.  Maternal gestational smoking, diabetes, alcohol drinking, pre-pregnancy obesity and the risk of cryptorchidism: a systematic review and meta-analysis of observational studies.

Authors:  Lin Zhang; Xing-Huan Wang; Xin-Min Zheng; Tong-Zu Liu; Wei-Bin Zhang; Hang Zheng; Mi-Feng Chen
Journal:  PLoS One       Date:  2015-03-23       Impact factor: 3.240

Review 4.  Does early orchidopexy improve fertility?

Authors:  Brittney L Hanerhoff; Charles Welliver
Journal:  Transl Androl Urol       Date:  2014-12
  4 in total

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