Literature DB >> 10932176

The NOTCH4 locus is associated with susceptibility to schizophrenia.

J Wei1, G P Hemmings.   

Abstract

Linkage disequilibrium mapping of the MHC region in 80 British parent-offspring trios showed that NOTCH4 was highly associated with schizophrenia. The A-->G substitution in the promoter region and the (CTG)n repeat in exon 1 of NOTCH4 may be candidate sites conferring susceptibility to schizophrenia.

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Year:  2000        PMID： 10932176     DOI： 10.1038/78044

Source DB:  PubMed          Journal:  Nat Genet        ISSN： 1061-4036            Impact factor:   38.330


  44 in total

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Review 10.  Common variants in polygenic schizophrenia.

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Journal:  Genome Biol       Date:  2009-09-29       Impact factor: 13.583
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