Literature DB >> 1093196

Alteration of bone marrow-thymus cell synergism in hereditary asplenic and adult splenctomiced mice.

L B Wargon, B B Lozzio, C J Wust.   

Abstract

The cooperation betweeen bone marrow (B) and thymus (T) cells was markedly impaired in mice with congenital asplenia. The deficiency of IgM producers could not be corrected by neotal transplantation of spleen cells. The use of T and B cells from splenectomized donors resulted in a marked shift from 19S to 7S antibody forming cells.

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Year:  1975        PMID: 1093196     DOI: 10.3181/00379727-148-38661

Source DB:  PubMed          Journal:  Proc Soc Exp Biol Med        ISSN: 0037-9727


  3 in total

1.  Effects of splenectomy on the humoral immune system. A study in neonatally and adult splenectomized mice.

Authors:  J Rozing; N H Brons; R Bennner
Journal:  Immunology       Date:  1978-05       Impact factor: 7.397

2.  Immunobiology of congenitally athymic-asplenic mice.

Authors:  M E Gershwin; A Ahmed; R M Ikeda; M Shifrine; F Wilson
Journal:  Immunology       Date:  1978-04       Impact factor: 7.397

3.  Hereditary asplenic-athymic mice: transplantation of human myelogenous leukemic cells.

Authors:  B B Lozzio; E A Machado; C B Lozzio; S Lair
Journal:  J Exp Med       Date:  1976-01-01       Impact factor: 14.307

  3 in total

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