| Literature DB >> 1093179 |
Abstract
Many pairs of genes whose gene products are functionally related lie either 90 degrees or 180 degrees apart on the circular map of the E. coli chromosome. A mechanism of evolution is proposed that involves two sequential duplications of an ancestral genome, followed by mutation and divergence of function of replicate genes.Entities:
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Year: 1975 PMID: 1093179 PMCID: PMC432532 DOI: 10.1073/pnas.72.4.1354
Source DB: PubMed Journal: Proc Natl Acad Sci U S A ISSN: 0027-8424 Impact factor: 11.205