Literature DB >> 109306

alpha-Amanitin: inactivation by bovine lactoperoxidase.

P W Morris, K M Kelley, W G Logas.   

Abstract

The principle amatoxin, alpha-amanitin, is found to be extremely sensitive toward lactoperoxidase catalyzed degradation, rather than iodination, of the indole nucleus. Extensive attenuation of inhibitor potency against eukaryotic DNA-dependent RNA polymerase II accompanies the treatment of alpha-amanitin with lactoperoxidase, iodide and hydrogen peroxide.

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Year:  1979        PMID: 109306     DOI: 10.1007/bf01960335

Source DB:  PubMed          Journal:  Experientia        ISSN: 0014-4754


  17 in total

Review 1.  Eukaryotic nuclear RNA polymerases.

Authors:  P Chambon
Journal:  Annu Rev Biochem       Date:  1975       Impact factor: 23.643

2.  Occurence of phallotoxins in American collections of Amanita virosa.

Authors:  S H Malak
Journal:  Planta Med       Date:  1976-02       Impact factor: 3.352

3.  Analysis of the toxins of amanitin-containing mushrooms.

Authors:  H Faulstich; D Georgopoulos; M Bloching; T Wieland
Journal:  Z Naturforsch C Biosci       Date:  1974 Jan-Feb

Review 4.  The toxic peptides of Amanita phalloides.

Authors:  T Wieland
Journal:  Fortschr Chem Org Naturst       Date:  1967

5.  The effects of amanitin poisoning on mouse kidney.

Authors:  L Fiume; V Marinozzi; F Nardi
Journal:  Br J Exp Pathol       Date:  1969-06

6.  Roentgenographic features of mushroom (Amanita) poisoning.

Authors:  L G Hanelin; A A Moss
Journal:  Am J Roentgenol Radium Ther Nucl Med       Date:  1975-12

7.  Biochemistry of the amatoxins: preparation and characterization of a stably iodinated alpha-amanitin.

Authors:  P W Morris; D L Venton; K M Kelley
Journal:  Biochemistry       Date:  1978-02-21       Impact factor: 3.162

8.  Phalloidin-induced actin polymerization in the cytoplasm of cultured cells interferes with cell locomotion and growth.

Authors:  J Wehland; M Osborn; K Weber
Journal:  Proc Natl Acad Sci U S A       Date:  1977-12       Impact factor: 11.205

Review 9.  Peroxidase-catalyzed halogenation.

Authors:  M Morrison; G R Schonbaum
Journal:  Annu Rev Biochem       Date:  1976       Impact factor: 23.643

10.  Interaction of phalloidin with actin.

Authors:  A M Lengsfeld; I Löw; T Wieland; P Dancker; W Hasselbach
Journal:  Proc Natl Acad Sci U S A       Date:  1974-07       Impact factor: 11.205

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  2 in total

Review 1.  Antimicrobial actions of dual oxidases and lactoperoxidase.

Authors:  Demba Sarr; Eszter Tóth; Aaron Gingerich; Balázs Rada
Journal:  J Microbiol       Date:  2018-06-01       Impact factor: 3.422

2.  Sensitivity of Carrot Cell Cultures and RNA Polymerase II to Amatoxins : Evidence for the Inactivation of 6'-Hydroxyamatoxins.

Authors:  M C Little; J F Preston
Journal:  Plant Physiol       Date:  1985-02       Impact factor: 8.340

  2 in total

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