| Literature DB >> 10928142 |
N Mizukawa1, K Sawaki, E Yamachika, J Fukunaga, T Ueno, S Takagi, T Sugahara.
Abstract
The purpose of this study was to demonstrate immunohistochemically the localization and distribution of human beta-defensin-2 (HBD-2), a peptide with antimicrobial activity, in oral carcinoma tissues. Tissue samples were embedded in paraffin, and HBD-2 was immunostained by the streptavidin-biotin coupled peroxidase method. Cancer cells in the cornified region of well differentiated squamous cell carcinomas were stained intensely. Stained cancer cells detected by anti-HBD-2 antibody were scattered among the cells of the non-cornified region.Entities:
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Year: 2000 PMID： 10928142
Source DB: PubMed Journal: Anticancer Res ISSN： 0250-7005 Impact factor: 2.480