Literature DB >> 10925410

Evaluation of antidiarrhoeal profile of Jussiaea suffruticosa linn. extract in rats.

T Murugesan1, L Ghosh, K Mukherjee, J Das, M Pal, B P Saha.   

Abstract

The antidiarrhoeal potential of a methanol extract of the aerial parts of Jussiaea suffruticosa Linn. (MEJS) was studied with several experimental models of diarrhoea in rats. MEJS treated rats showed significant inhibitory activity against castor oil induced diarrhoea and PGE(2) induced enteropooling. It also showed a significant reduction in gastrointestinal motility following a charcoal meal in rats. The extract exhibited significant antidiarrhoeal potential at doses of 100,200 and 300 mg/kg in all the animal models and thus established the efficacy of MEJS as a potent antidiarrhoeal agent. Copyright 2000 John Wiley & Sons, Ltd.

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Year:  2000        PMID： 10925410     DOI： 10.1002/1099-1573(200008)14:5<381::aid-ptr590>3.0.co;2-p

Source DB:  PubMed          Journal:  Phytother Res        ISSN： 0951-418X            Impact factor:   5.878


  6 in total

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Authors:  J A J Sunilson; K Anandarajagopal; A V A G Kumari; S Mohan
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5.  Antidiarrheal activity of ethanolic extract of Manihot esculenta Crantz leaves in Wistar rats.

Authors:  Satish E Bahekar; Ranjana S Kale
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6.  Identification of Digestive Enzyme Inhibitors from Ludwigia octovalvis (Jacq.) P.H.Raven.

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  6 in total

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