Literature DB >> 10925022

Hypoglycaemic activity of Ocimum gratissimum in rats.

J C Aguiyi1, C I Obi, S S Gang, A C Igweh.   

Abstract

The hypoglycaemic effect of the methanolic extract of Ocimum gratissimum leaves was evaluated in normal and alloxan-induced diabetic rats. Intraperitoneal injection of the extract (400 mg/kg) significantly reduced plasma levels both in normal and diabetic rats by 56 and 68%, respectively.

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Year:  2000        PMID： 10925022     DOI： 10.1016/s0367-326x(00)00143-x

Source DB:  PubMed          Journal:  Fitoterapia        ISSN： 0367-326X            Impact factor:   2.882


  15 in total

Review 1.  The globalization of traditional medicine in northern peru: from shamanism to molecules.

Authors:  Rainer W Bussmann
Journal:  Evid Based Complement Alternat Med       Date:  2013-12-28       Impact factor: 2.629

2.  Ocimum gratissimum enhances insulin sensitivity in male Wistar rats with dexamethasone-induced insulin resistance.

Authors:  Shehu-Tijani Toyin Shittu; Taye Jemilat Lasisi; Seyid Alli-Sisse Shittu; Adeyinka Adeyemi; Tolulope James Adeoye; AbdulRasak Akinola Alada
Journal:  J Diabetes Metab Disord       Date:  2021-07-13

3.  Ocimum gratissimum Aqueous Extract Protects H9c2 Myocardiac Cells from H(2)O(2)-Induced Cell Apoptosis through Akt Signalling.

Authors:  Mu-Jang Lee; Han-Min Chen; Bor-Show Tzang; Chiu-Wen Lin; Chau-Jong Wang; Jer-Yuh Liu; Shao-Hsuan Kao
Journal:  Evid Based Complement Alternat Med       Date:  2010-08-30       Impact factor: 2.629

4.  [Ethnobotanical study of plants used in the treatment of diabetes in the traditional medicine of Maritime Region, Togo].

Authors:  Gbekley Efui Holaly; Karou Damintoti Simplice; Gnoula Charlemagne; Agbodeka Kodjovi; Anani Kokou; Tchacondo Tchadjobo; Agbonon Amegnona; Batawila Komlan; Simpore Jacques
Journal:  Pan Afr Med J       Date:  2015-04-30

5.  Ocimum gratissmum aqueous extract reduces plasma lipid in hypercholesterol-fed hamsters.

Authors:  Pei-Yu Chao; James A Lin; Wei-Jen Ting; Hsueh-Hui Lee; Kuanghui Hsieh; Yung-Wei Chiu; Te-Jen Lai; Jin-Ming Hwang; Je-rYuh Liu; Chih-Yang Huang
Journal:  Int J Med Sci       Date:  2016-10-18       Impact factor: 3.738

6.  Amelioration of estrogen-deficiency-induced obesity by Ocimum gratissimum.

Authors:  Pei-Yu Chao; Tsay-I Chiang; I-Chang Chang; Fang-Ling Tsai; Hsueh-Hui Lee; Kuanghui Hsieh; Yung-Wei Chiu; Te-Jen Lai; Jer-Yuh Liu; Li-Sung Hsu; Yang-Chia Shih
Journal:  Int J Med Sci       Date:  2017-07-20       Impact factor: 3.738

7.  Herbal Supplement Ameliorates Cardiac Hypertrophy in Rats with CCl(4)-Induced Liver Cirrhosis.

Authors:  Ping-Chun Li; Yung-Wei Chiu; Yueh-Min Lin; Cecilia Hsuan Day; Guang-Yuh Hwang; Peiying Pai; Fuu-Jen Tsai; Chang-Hai Tsai; Yu-Chun Kuo; Hsiao-Chuan Chang; Jer-Yuh Liu; Chih-Yang Huang
Journal:  Evid Based Complement Alternat Med       Date:  2012-11-06       Impact factor: 2.629

8.  Effect of aqueous leaves extract of Ocimum gratissimum on hematological parameters in rats.

Authors:  Oe Ofem; Ej Ani; Ae Eno
Journal:  Int J Appl Basic Med Res       Date:  2012-01

9.  Aqueous leaf extract of Ocimum gratissimum improves hematological parameters in alloxan-induced diabetic rats via its antioxidant properties.

Authors:  Shehu-Tijani Toyin Shittu; Wahab A Oyeyemi; Taye J Lasisi; Seyid Alli-Siise Shittu; Temitope T Lawal; Samuel T Olujobi
Journal:  Int J Appl Basic Med Res       Date:  2016 Apr-Jun

10.  Antidiabetic and antihyperlipidemic effects of aqueous extract of Parquetina nigrescens in streptozotocin-nicotinamide induced type 2 diabetic rats.

Authors:  Fatimoh Idowu Ojuade; Olufunke Esan Olorundare; Olatunde Babatunde Akanbi; Saheed Olanrewaju Afolabi; Anoka Ayembe Njan
Journal:  Heliyon       Date:  2021-06-21
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