Literature DB >> 10923849

Antisweet natural products. XV. Structures of Jegosaponins A-D from Styrax japonica Sieb. et Zucc.

K Yoshikawa1, H Hirai, M Tanaka, S Arihara.   

Abstract

From the fresh fruits of Strrax japonica Sieb. et Zucc., four new triterpenoid glycosides, named jegosaponins A-D (1-4), were isolated. Their structures were determined on the basis of spectroscopic data and chemical evidence. Compounds 1-4 are 3-O-tetraglycosides of barringtogenol C having an acetyl and a tigloyl or a (2Z)-hexenoyl groups at C-21, 22 and 28. The acylated saponins, 1-4, all showed antisweet activity.

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Year:  2000        PMID: 10923849     DOI: 10.1248/cpb.48.1093

Source DB:  PubMed          Journal:  Chem Pharm Bull (Tokyo)        ISSN: 0009-2363            Impact factor:   1.645


  6 in total

1.  Activity of tumor necrosis factor-α blocked by phytoglycoprotein (38 kDa) at initiation stage in N-nitrosodiethylamine-induced ICR mice.

Authors:  Jin Lee; Kye-Taek Lim
Journal:  Mol Cell Biochem       Date:  2011-11-02       Impact factor: 3.396

2.  Inhibitory effect of phytoglycoprotein (38 kDa) on expression of matrix metalloproteinase-9 in 12-O-tetradecanoylphorbol-13-acetate-treated HepG2cells.

Authors:  Jin Lee; Kye-Taek Lim
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  2011-06-29       Impact factor: 3.000

3.  Inhibitory effect of SJSZ glycoprotein (38 kDa) on expression of heat shock protein 27 and 70 in chromium (VI)-treated hepatocytes.

Authors:  Jin Lee; Kye-Taek Lim
Journal:  Mol Cell Biochem       Date:  2011-07-28       Impact factor: 3.396

4.  Inductive effect of phytoglycoprotein (38 kDa) on G₀/G₁ arrest and apoptosis in diethylnitrosamine-treated ICR mice.

Authors:  Jin Lee; Kye-Taek Lim
Journal:  Mol Cell Biochem       Date:  2012-12-02       Impact factor: 3.396

5.  SJSZ glycoprotein (38 kDa) modulates macrophage type 1/2-related factors at hepatocarcinogenic stage in N-nitrosodiethylamine-treated Balb/c.

Authors:  Jin Lee; Kye-Taek Lim
Journal:  Mol Cell Biochem       Date:  2012-09-07       Impact factor: 3.396

6.  Toxicity of Jegosaponins A and B from Styrax japonica Siebold et al. Zuccarini in Prostate Cancer Cells and Zebrafish Embryos Resulting from Increased Membrane Permeability.

Authors:  Moe Nishimura; Hiroyuki Fuchino; Kaoru Takayanagi; Hitomi Kawakami; Hiroko Nakayama; Nobuo Kawahara; Yasuhito Shimada
Journal:  Int J Mol Sci       Date:  2021-06-14       Impact factor: 5.923

  6 in total

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