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Literature DB >> 10921988

Lactoferrin and eosinophilic cationic protein in nasal secretions of patients with experimental rhinovirus colds, natural colds, and presumed acute community-acquired bacterial sinusitis.

M D Niehaus¹, J M Gwaltney, J O Hendley, M J Newman, P W Heymann, G P Rakes, T A Platts-Mills, R L Guerrant.

Abstract

To distinguish sinusitis from uncomplicated "colds," we examined lactoferrin and eosinophilic cationic protein (ECP) in nasal secretions. Lactoferrin titers were >/=1:400 in 4% of persons with uncomplicated colds and controls but in 79% of persons with sinusitis or purulent sputa. ECP levels were >200 ng/ml in 61% of persons with colds and >3,000 ng/ml in 62% of persons with sinusitis. Nasal lactoferrin helps distinguish sinusitis from colds.

Entities: Disease Species

Mesh：

Substances：

Year: 2000 PMID： 10921988 PMCID： PMC87198

Source DB: PubMed Journal: J Clin Microbiol ISSN： 0095-1137 Impact factor: 5.948

15 in total

1. Chronic sinusitis: risk factors for extensive disease.

Authors: G E Hoover; L J Newman; T A Platts-Mills; C D Phillips; C W Gross; L M Wheatley
Journal: J Allergy Clin Immunol Date: 1997-08 Impact factor: 10.793

Review 2. Acute community-acquired sinusitis.

Authors: J M Gwaltney
Journal: Clin Infect Dis Date: 1996-12 Impact factor: 9.079

3. Measurement of fecal lactoferrin as a marker of fecal leukocytes.

Authors: R L Guerrant; V Araujo; E Soares; K Kotloff; A A Lima; W H Cooper; A G Lee
Journal: J Clin Microbiol Date: 1992-05 Impact factor: 5.948

4. Human nasal polyp epithelial basophil/mast cell and eosinophil colony-stimulating activity. The effect is T-cell-dependent.

Authors: M Ohnishi; J Ruhno; J Bienenstock; R Milner; J Dolovich; J A Denburg
Journal: Am Rev Respir Dis Date: 1988-09

5. Occurrence of asymptomatic sinusitis in common cold and other acute ENT-infections.

Authors: O Berg; C Carenfelt; G Rystedt; A Anggård
Journal: Rhinology Date: 1986-09 Impact factor: 3.681

6. Computed tomographic study of the common cold.

Authors: J M Gwaltney; C D Phillips; R D Miller; D K Riker
Journal: N Engl J Med Date: 1994-01-06 Impact factor: 91.245

7. Comparison of fecal lactoferrin latex agglutination assay and methylene blue microscopy for detection of fecal leukocytes in Clostridium difficile-associated disease.

Authors: W H Yong; A R Mattia; M J Ferraro
Journal: J Clin Microbiol Date: 1994-05 Impact factor: 5.948

Review 4. Utility of animal and in vivo experimental infection of humans with rhinoviruses in the development of therapeutic agents for viral exacerbations of asthma and chronic obstructive pulmonary disease.

Authors: Alfred M Del Vecchio; Patrick J Branigan; Elliot S Barnathan; Susan K Flavin; Philip E Silkoff; Ronald B Turner
Journal: Pulm Pharmacol Ther Date: 2014-11-13 Impact factor: 3.410

4 in total

Lactoferrin and eosinophilic cationic protein in nasal secretions of patients with experimental rhinovirus colds, natural colds, and presumed acute community-acquired bacterial sinusitis.

1. Chronic sinusitis: risk factors for extensive disease.

Review 2. Acute community-acquired sinusitis.

3. Measurement of fecal lactoferrin as a marker of fecal leukocytes.

4. Human nasal polyp epithelial basophil/mast cell and eosinophil colony-stimulating activity. The effect is T-cell-dependent.

5. Occurrence of asymptomatic sinusitis in common cold and other acute ENT-infections.

6. Computed tomographic study of the common cold.

7. Comparison of fecal lactoferrin latex agglutination assay and methylene blue microscopy for detection of fecal leukocytes in Clostridium difficile-associated disease.

8. Chronic sinusitis. Relationship of computed tomographic findings to allergy, asthma, and eosinophilia.

9. Eosinophil cationic protein in serum and nasal washes from wheezing infants and children.

10. Evidence for distinct cytokine expression in allergic versus nonallergic chronic sinusitis.

1. Collection of nasal secretions for immunological analysis.

Review 2. Analysing the eosinophil cationic protein--a clue to the function of the eosinophil granulocyte.

3. Infection, eosinophilia and childhood asthma.

Review 4. Utility of animal and in vivo experimental infection of humans with rhinoviruses in the development of therapeutic agents for viral exacerbations of asthma and chronic obstructive pulmonary disease.