R Zhang1, D Fang, D Zhang. 1. Department of Thoracic Surgery, Cancer Institute (Hospital), Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing.
Abstract
OBJECTIVE: To evaluate the results of surgical treatment for carcinoma of the gastric cardia and the prognostic factors. METHODS: The prognostic factors were assessed with 5-year survival rates which was estimated using life table method in 1832 cases. The difference between groups was assessed by the log rank test. RESULTS: The overall resection rate was 76.3% and the radical resection rate 53.4%. The overall 5-year survival rate was 23.5% while in patients treated with curative resection it was 29.9%. The 5-year survival rate was 29.4% in patients received preoperative radiation and 21.5% in patients treated with surgery alone (P > 0.05). Patients whose upper margin of resection was longer than 5 cm away from the tumor had higher 5-year survival rate (25.8%) than those with margin of resection less than 5 cm (18.4%). The difference was statistically significant (P < 0.05). CONCLUSION: Preoperative radiation can increase the survival rate, but it was not statistically significant. Increasing the margin of resection to > 5 cm can improve survival.
OBJECTIVE: To evaluate the results of surgical treatment for carcinoma of the gastric cardia and the prognostic factors. METHODS: The prognostic factors were assessed with 5-year survival rates which was estimated using life table method in 1832 cases. The difference between groups was assessed by the log rank test. RESULTS: The overall resection rate was 76.3% and the radical resection rate 53.4%. The overall 5-year survival rate was 23.5% while in patients treated with curative resection it was 29.9%. The 5-year survival rate was 29.4% in patients received preoperative radiation and 21.5% in patients treated with surgery alone (P > 0.05). Patients whose upper margin of resection was longer than 5 cm away from the tumor had higher 5-year survival rate (25.8%) than those with margin of resection less than 5 cm (18.4%). The difference was statistically significant (P < 0.05). CONCLUSION: Preoperative radiation can increase the survival rate, but it was not statistically significant. Increasing the margin of resection to > 5 cm can improve survival.