| Literature DB >> 10920422 |
B A Cruz1, E D Queiroz, S V Nunes, A Cruz Filho, G B Campos, E L Monteiro, H Crivellari.
Abstract
Interferon-beta (IFN-beta) is administered for treatment of multiple sclerosis (MS). We report on a woman with MS who presented with severe Raynaud's phenomenon, livedo-reticularis and digital necrosis two weeks after beginning therapy with IFN-beta. Symptoms improved after the IFN-beta was discontinued and anticoagulation associated with cyclophosphamide and corticoid were introduced. Raynaud's phenomenon is probably a side effect of IFN-beta therapy for multiple sclerosis.Entities:
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Year: 2000 PMID: 10920422 DOI: 10.1590/s0004-282x2000000300025
Source DB: PubMed Journal: Arq Neuropsiquiatr ISSN: 0004-282X Impact factor: 1.420