| Literature DB >> 10919100 |
S K Mitra1, S J Seshadri, M V Venkataranganna, S Gopumadhavan, U V Udupa, D N Sarma.
Abstract
The effect of HD-03 a herbal preparation was studied on galactosamine (400 mg/kg b.wt., i.p.) induced hepatotoxicity in rats. Animals were pre-treated for 14 days with HD-03 and compared against untreated group for SGPT, SGOT, serum bilirubin and liver glycogen. Histopathology of liver lobes was considered to evaluate the extent of hepatic injury induced by galactosamine. These were reversed by HD-03 pre-treatment. HD-03 provided convincing evidence of hepatoprotection against galactosamine induced hapatotoxicity.Entities:
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Year: 2000 PMID： 10919100
Source DB: PubMed Journal: Indian J Physiol Pharmacol ISSN： 0019-5499