UNLABELLED: Dengue-Fever is a mosquito transmitted viral disease. It is endemic mainly in South-East Asia and Africa. The clinical manifestation is divided into different stages. Ocular manifestations in travellers have been rarely reported. PATIENTS: We present the cases of two patients, having just returned from a trip to Thailand. During their trip they had fallen ill with symptoms of classic dengue-fever. FINDINGS: On examination visual acuity had decreased in both patients. In one patient we detected a relative central scotoma in perimetry and reduced amplitudes in VEP. In indirect ophthalmoscopy we found intraretinal haemorrhages, foveal lesions in the pigment epithelium, cotton-wool spots and a maculopathy. The fluorescein angiographic findings included extravasation in the macular region and block fluorescence. The diagnosis was confirmed by a rise in Dengue-fever antibody titre and the detection of flavivirus IgM antibodies. CONCLUSION: Dengue-fever and its ocular manifestation in Europeans is a rare condition. Expanding tourism to tropical countries may lead to an increasing number of cases.
UNLABELLED: Dengue-Fever is a mosquito transmitted viral disease. It is endemic mainly in South-East Asia and Africa. The clinical manifestation is divided into different stages. Ocular manifestations in travellers have been rarely reported. PATIENTS: We present the cases of two patients, having just returned from a trip to Thailand. During their trip they had fallen ill with symptoms of classic dengue-fever. FINDINGS: On examination visual acuity had decreased in both patients. In one patient we detected a relative central scotoma in perimetry and reduced amplitudes in VEP. In indirect ophthalmoscopy we found intraretinal haemorrhages, foveal lesions in the pigment epithelium, cotton-wool spots and a maculopathy. The fluorescein angiographic findings included extravasation in the macular region and block fluorescence. The diagnosis was confirmed by a rise in Dengue-fever antibody titre and the detection of flavivirus IgM antibodies. CONCLUSION:Dengue-fever and its ocular manifestation in Europeans is a rare condition. Expanding tourism to tropical countries may lead to an increasing number of cases.
Authors: Tatty E Setiati; Albert T A Mairuhu; Penelopie Koraka; Mohamed Supriatna; Melvin R Mac Gillavry; Dees P M Brandjes; Albert D M E Osterhaus; Jos W M van der Meer; Eric C M van Gorp; Augustinus Soemantri Journal: BMC Infect Dis Date: 2007-03-26 Impact factor: 3.090
Authors: David P L Chan; Stephen C B Teoh; Colin S H Tan; Gerard K M Nah; Rajesh Rajagopalan; Manjunath K Prabhakaragupta; Caroline K L Chee; Tock H Lim; Kong Y Goh Journal: Emerg Infect Dis Date: 2006-02 Impact factor: 6.883
Authors: Thaís Sousa Mendes; Edmundo Frota de Almeida Sobrinho; Alexandre Antonio Marques Rosa; Laiza Medeiros dos Anjos; Genilma Matos da Costa; Givago da Silva Souza; Bruno Duarte Gomes; Cézar Akiyoshi Saito; Manoel da Silva Filho; Luiz Carlos de Lima Silveira Journal: Doc Ophthalmol Date: 2009-06-18 Impact factor: 1.854