Literature DB >> 10916138

Of mice and men: hybridoma and recombinant antibodies.

M Little1, S M Kipriyanov, F Le Gall, G Moldenhauer.   

Abstract

Thousands of mouse monoclonal antibodies have been produced from hybridomas over the past 25 years. The same technique can now be used to clone human antibodies from transgenic mice. Full-length antibodies and recombinant fragments engineered for various diagnostic and therapeutic applications can be obtained in reasonably large amounts after expression in mammalian cells, milk and plants.

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Year:  2000        PMID： 10916138     DOI： 10.1016/s0167-5699(00)01668-6

Source DB:  PubMed          Journal:  Immunol Today        ISSN： 0167-5699


  26 in total

Review 1.  Generation and production of engineered antibodies.

Authors:  Sergey M Kipriyanov; Fabrice Le Gall
Journal:  Mol Biotechnol       Date:  2004-01       Impact factor: 2.695

Review 2.  FLT3 antibody-based therapeutics for leukemia therapy.

Authors:  Yiwen Li; Zhenping Zhu
Journal:  Int J Hematol       Date:  2005-08       Impact factor: 2.490

Review 3.  Protein-Catalyzed Capture Agents.

Authors:  Heather D Agnew; Matthew B Coppock; Matthew N Idso; Bert T Lai; JingXin Liang; Amy M McCarthy-Torrens; Carmen M Warren; James R Heath
Journal:  Chem Rev       Date:  2019-03-06       Impact factor: 60.622

4.  Clonal diversification in OspA-specific antibodies from peripheral circulation of a chronic Lyme arthritis patient.

Authors:  Srimoyee Ghosh; Brigitte T Huber
Journal:  J Immunol Methods       Date:  2007-02-06       Impact factor: 2.303

5.  Humanization of Camelid Single-Domain Antibodies.

Authors:  Traian Sulea
Journal:  Methods Mol Biol       Date:  2022

6.  Phage display of human antibodies from a patient suffering from coeliac disease and selection of isotype-specific scFv against gliadin.

Authors:  Claudio Rhyner; Michael Weichel; Philipp Hübner; Gernot Achatz; Kurt Blaser; Reto Crameri
Journal:  Immunology       Date:  2003-10       Impact factor: 7.397

7.  Cloned transgenic farm animals produce a bispecific antibody for T cell-mediated tumor cell killing.

Authors:  Ludger Grosse-Hovest; Sigrid Müller; Rosa Minoia; Eckhard Wolf; Valeri Zakhartchenko; Hendrik Wenigerkind; Caroline Lassnig; Urban Besenfelder; Mathias Müller; Simon D Lytton; Gundram Jung; Gottfried Brem
Journal:  Proc Natl Acad Sci U S A       Date:  2004-04-22       Impact factor: 11.205

8.  CD176 single-chain variable antibody fragment inhibits the adhesion of cancer cells to endothelial cells and hepatocytes.

Authors:  Jiangnan Liu; Bin Yi; Zhe Zhang; Yi Cao
Journal:  Front Med       Date:  2016-04-18       Impact factor: 4.592

9.  A rapid and efficient single-cell manipulation method for screening antigen-specific antibody-secreting cells from human peripheral blood.

Authors:  Aishun Jin; Tatsuhiko Ozawa; Kazuto Tajiri; Tsutomu Obata; Sachiko Kondo; Koshi Kinoshita; Shinichi Kadowaki; Kazuo Takahashi; Toshiro Sugiyama; Hiroyuki Kishi; Atsushi Muraguchi
Journal:  Nat Med       Date:  2009-08-16       Impact factor: 53.440

10.  Antibody-Drug Conjugate to Treat Meningiomas.

Authors:  Kai Chen; Yingnan Si; Jianfa Ou; Jia-Shiung Guan; Seulhee Kim; Patrick Ernst; Ya Zhang; Lufang Zhou; Xiaosi Han; Xiaoguang Margaret Liu
Journal:  Pharmaceuticals (Basel)       Date:  2021-05-02
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