| Literature DB >> 10915061 |
J Ma1, E Weiss, D E Kyle, H Ziffer.
Abstract
A series of 14-substituted-artemisinin and 9-epiartemisinin derivatives was prepared by a titanium-tetrachloride catalyzed addition of trimethylsilyl enol ethers to artemisitene. Several compounds were four to seven times more active than artemisinin against Plasmodium falciparum.Entities:
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Year: 2000 PMID： 10915061 DOI： 10.1016/s0960-894x(00)00297-3
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823