Literature DB >> 10915055

Solid phase synthesis of aminoboronic acids: potent inhibitors of the hepatitis C virus NS3 proteinase.

R M Dunsdon1, J R Greening, P S Jones, S Jordan, F X Wilson.   

Abstract

Use of a resin bound diol as a boronic acid protecting group has been developed to allow the parallel synthesis of potent inhibitors of the hepatitis C virus NS3 serine proteinase.

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Year:  2000        PMID： 10915055     DOI： 10.1016/s0960-894x(00)00284-5

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN： 0960-894X            Impact factor:   2.823


  5 in total

1.  Synthesis and reactivity of solid-supported organotrifluoroborates in Suzuki cross-coupling.

Authors:  Virginie Colombel; Marc Presset; Daniel Oehlrich; Frederik Rombouts; Gary A Molander
Journal:  Org Lett       Date:  2012-03-09       Impact factor: 6.005

2.  A solid-state (11)b NMR and computational study of boron electric field gradient and chemical shift tensors in boronic acids and boronic esters.

Authors:  Joseph W E Weiss; David L Bryce
Journal:  J Phys Chem A       Date:  2010-04-22       Impact factor: 2.781

3.  A solid-phase approach for the synthesis of α-aminoboronic acid peptides.

Authors:  Blake E Daniels; Craig E Stivala
Journal:  RSC Adv       Date:  2018-01-16       Impact factor: 4.036

4.  Diversity-oriented synthesis of peptide-boronic acids by a versatile building-block approach.

Authors:  Stefan P A Hinkes; Severin Kämmerer; Christian D P Klein
Journal:  Chem Sci       Date:  2020-08-21       Impact factor: 9.825

5.  Facile synthesis of α-aminoboronic acids from amines and potassium acyltrifluoroborates (KATs) via trifluoroborate-iminiums (TIMs).

Authors:  Tomoya Shiro; Anne Schuhmacher; Moritz K Jackl; Jeffrey W Bode
Journal:  Chem Sci       Date:  2018-05-16       Impact factor: 9.825
  5 in total

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