Literature DB >> 1091161

Depression and anxiety in heroin addicts: a placebo-controlled study of doxepin in combination with methadone.

G E Woody, C P O'Brien, K Rickels.   

Abstract

Narcotic addicts may manifest symptoms of depression that aggravate their addiction. In this double-blind study of 35 mildly depressed patients in a methadone maintenance program, subjects who received doxepin improved significantly more than control subjects. Even in this short-term study, the reduction in depression was associated with a trend toward better performance in other areas of rehabilitation.

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Year:  1975        PMID： 1091161     DOI： 10.1176/ajp.132.4.447

Source DB:  PubMed          Journal:  Am J Psychiatry        ISSN： 0002-953X            Impact factor:   18.112


  11 in total

1.  Superior methadone treatment outcome in Hmong compared with non-Hmong patients.

Authors:  Gavin Bart; Qi Wang; James S Hodges; Chris Nolan; Gregory Carlson
Journal:  J Subst Abuse Treat       Date:  2012-01-28

Review 2.  Treatment of substance abusing patients with comorbid psychiatric disorders.

Authors:  Thomas M Kelly; Dennis C Daley; Antoine B Douaihy
Journal:  Addict Behav       Date:  2011-09-14       Impact factor: 3.913

3.  Opiate exposure and withdrawal dynamically regulate mRNA expression in the serotonergic dorsal raphe nucleus.

Authors:  J W Lunden; L G Kirby
Journal:  Neuroscience       Date:  2013-09-20       Impact factor: 3.590

4.  Stress, craving and mood as predictors of early dropout from opioid agonist therapy.

Authors:  Leigh V Panlilio; Samuel W Stull; William J Kowalczyk; Karran A Phillips; Jennifer R Schroeder; Jeremiah W Bertz; Massoud Vahabzadeh; Jia-Ling Lin; Mustapha Mezghanni; Edward V Nunes; David H Epstein; Kenzie L Preston
Journal:  Drug Alcohol Depend       Date:  2019-07-16       Impact factor: 4.492

5.  The association between naltrexone treatment and symptoms of depression in opioid-dependent patients.

Authors:  David J Mysels; Wendy Y Cheng; Edward V Nunes; Maria A Sullivan
Journal:  Am J Drug Alcohol Abuse       Date:  2010-12-30       Impact factor: 3.829

6.  Morphine history sensitizes postsynaptic GABA receptors on dorsal raphe serotonin neurons in a stress-induced relapse model in rats.

Authors:  D R Staub; J W Lunden; A M Cathel; E L Dolben; L G Kirby
Journal:  Psychoneuroendocrinology       Date:  2011-11-01       Impact factor: 4.905

Review 7.  Contributions of serotonin in addiction vulnerability.

Authors:  L G Kirby; F D Zeeb; C A Winstanley
Journal:  Neuropharmacology       Date:  2011-04-03       Impact factor: 5.250

8.  Psychiatric comorbidity and treatment outcomes in patients with opioid use disorder: Results from a multisite trial of buprenorphine-naloxone and methadone.

Authors:  Yuhui Zhu; Larissa J Mooney; Caroline Yoo; Elizabeth A Evans; Annemarie Kelleghan; Andrew J Saxon; Megan E Curtis; Yih-Ing Hser
Journal:  Drug Alcohol Depend       Date:  2021-08-28       Impact factor: 4.492

Review 9.  Doxepin up-to-date: a review of its pharmacological properties and therapeutic efficacy with particular reference to depression.

Authors:  R M Pinder; R N Brogden; T M Speight; G S Avery
Journal:  Drugs       Date:  1977-03       Impact factor: 9.546

Review 10.  Treating depression in substance abusers.

Authors:  Edward V Nunes; Frances R Levin
Journal:  Curr Psychiatry Rep       Date:  2006-10       Impact factor: 8.081
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