Literature DB >> 10908912

Mitochondrial DNA haplogroups and susceptibility to AD and dementia with Lewy bodies.

P F Chinnery1, G A Taylor, N Howell, R M Andrews, C M Morris, R W Taylor, I G McKeith, R H Perry, J A Edwardson, D M Turnbull.   

Abstract

The authors analyzed the relationship between nuclear genetic risk factors (apolipoprotein E genotype) and mitochondrial DNA (mtDNA) sequence variants in pathologically proved cases of AD (n = 185), dementia with Lewy bodies (DLB; n = 84), and control subjects (n = 179). Specific European mtDNA haplogroups and the A4336G mutation were not associated with an increased risk of AD. mtDNA haplogroup H was overrepresented in the DLB patients when compared with control subjects. Additional studies are needed to clarify the significance of the association.

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Year:  2000        PMID： 10908912     DOI： 10.1212/wnl.55.2.302

Source DB:  PubMed          Journal:  Neurology        ISSN： 0028-3878            Impact factor:   9.910


  40 in total

1.  Point mutations of the mtDNA control region in normal and neurodegenerative human brains.

Authors:  P F Chinnery; G A Taylor; N Howell; D T Brown; T J Parsons; D M Turnbull
Journal:  Am J Hum Genet       Date:  2000-12-21       Impact factor: 11.025

2.  Reduced-median-network analysis of complete mitochondrial DNA coding-region sequences for the major African, Asian, and European haplogroups.

Authors:  Corinna Herrnstadt; Joanna L Elson; Eoin Fahy; Gwen Preston; Douglass M Turnbull; Christen Anderson; Soumitra S Ghosh; Jerrold M Olefsky; M Flint Beal; Robert E Davis; Neil Howell
Journal:  Am J Hum Genet       Date:  2002-04-05       Impact factor: 11.025

3.  Association between mitochondrial DNA variations and Alzheimer's disease in the ADNI cohort.

Authors:  Anita Lakatos; Olga Derbeneva; Danny Younes; David Keator; Trygve Bakken; Maria Lvova; Marty Brandon; Guia Guffanti; Dora Reglodi; Andrew Saykin; Michael Weiner; Fabio Macciardi; Nicholas Schork; Douglas C Wallace; Steven G Potkin
Journal:  Neurobiol Aging       Date:  2010-06-11       Impact factor: 4.673

4.  The power to detect disease associations with mitochondrial DNA haplogroups.

Authors:  David C Samuels; Andrew D Carothers; Robin Horton; Patrick F Chinnery
Journal:  Am J Hum Genet       Date:  2006-02-17       Impact factor: 11.025

Review 5.  The Alzheimer's disease mitochondrial cascade hypothesis: progress and perspectives.

Authors:  Russell H Swerdlow; Jeffrey M Burns; Shaharyar M Khan
Journal:  Biochim Biophys Acta       Date:  2013-09-23

6.  Mitochondrial DNA haplogroups in early-onset Alzheimer's disease and frontotemporal lobar degeneration.

Authors:  Johanna Krüger; Reetta Hinttala; Kari Majamaa; Anne M Remes
Journal:  Mol Neurodegener       Date:  2010-02-02       Impact factor: 14.195

Review 7.  Mitochondria as therapeutic targets for cancer stem cells.

Authors:  In Sung Song; Jeong Yu Jeong; Seung Hun Jeong; Hyoung Kyu Kim; Kyung Soo Ko; Byoung Doo Rhee; Nari Kim; Jin Han
Journal:  World J Stem Cells       Date:  2015-03-26       Impact factor: 5.326

8.  Retrospective analysis of phytoSERM for management of menopause-associated vasomotor symptoms and cognitive decline: a pilot study on pharmacogenomic effects of mitochondrial haplogroup and APOE genotype on therapeutic efficacy.

Authors:  Yiwei Wang; Gerson Hernandez; Wendy J Mack; Lon S Schneider; Fei Yin; Roberta D Brinton
Journal:  Menopause       Date:  2020-01       Impact factor: 2.953

9.  Evidence for sub-haplogroup h5 of mitochondrial DNA as a risk factor for late onset Alzheimer's disease.

Authors:  Aurelia Santoro; Valentina Balbi; Elisa Balducci; Chiara Pirazzini; Francesca Rosini; Francesca Tavano; Alessandro Achilli; Paola Siviero; Nadia Minicuci; Elena Bellavista; Michele Mishto; Stefano Salvioli; Francesca Marchegiani; Maurizio Cardelli; Fabiola Olivieri; Benedetta Nacmias; Andrea Maria Chiamenti; Luisa Benussi; Roberta Ghidoni; Giuseppina Rose; Carlo Gabelli; Giuliano Binetti; Sandro Sorbi; Gaetano Crepaldi; Giuseppe Passarino; Antonio Torroni; Claudio Franceschi
Journal:  PLoS One       Date:  2010-08-06       Impact factor: 3.240

10.  Mitochondria, cognitive impairment, and Alzheimer's disease.

Authors:  M Mancuso; V Calsolaro; D Orsucci; C Carlesi; A Choub; S Piazza; G Siciliano
Journal:  Int J Alzheimers Dis       Date:  2009-07-06
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