Literature DB >> 10907855

Structurally and functionally distinct mouse hsp70 family members Mot-1 and Mot-2 proteins are encoded by two alleles.

S C Kaul1, E Duncan, T Sugihara, R R Reddel, Y Mitsui, R Wadhwa.   

Abstract

The mouse mortalin proteins Mot-1 and Mot-2 differ by two amino acids in their carboxy-terminus. These proteins are differentially localized in the cell cytoplasm and have contrasting biological activities. The genetic relationship between Mot-1 and Mot-2 was deciphered by mouse family analyses. Mot-1 and Mot-2 segregated in F1 and F2 progeny, providing direct evidence that the two proteins are encoded by two alleles.

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Year:  2000        PMID： 10907855     DOI： 10.1093/dnares/7.3.229

Source DB:  PubMed          Journal:  DNA Res        ISSN： 1340-2838            Impact factor:   4.458


  6 in total

1.  An N-terminal region of mot-2 binds to p53 in vitro.

Authors:  S C Kaul; R R Reddel; Y Mitsui; R Wadhwa
Journal:  Neoplasia       Date:  2001 Mar-Apr       Impact factor: 5.715

2.  Mortalin is a prognostic factor of gastric cancer with normal p53 function.

Authors:  Koji Ando; Eiji Oki; Yan Zhao; Ayae Ikawa-Yoshida; Hiroyuki Kitao; Hiroshi Saeki; Yasue Kimura; Satoshi Ida; Masaru Morita; Tetsuya Kusumoto; Yoshihiko Maehara
Journal:  Gastric Cancer       Date:  2013-07-05       Impact factor: 7.370

Review 3.  An Hsp70 family chaperone, mortalin/mthsp70/PBP74/Grp75: what, when, and where?

Authors:  Renu Wadhwa; Kazunari Taira; Sunil C Kaul
Journal:  Cell Stress Chaperones       Date:  2002-07       Impact factor: 3.667

4.  Understanding the functional interplay between mammalian mitochondrial Hsp70 chaperone machine components.

Authors:  Arvind Vittal Goswami; Balasubramanyam Chittoor; Patrick D'Silva
Journal:  J Biol Chem       Date:  2010-04-14       Impact factor: 5.157

5.  Critical Role of Mortalin/GRP75 in Endothelial Cell Dysfunction Associated with Acute Lung Injury.

Authors:  Antony Leonard; Pei Yi Su; David I Yule; Arshad Rahman; Fabeha Fazal
Journal:  Shock       Date:  2020-08       Impact factor: 3.533

6.  Colocalisation of CD9 and mortalin in CD9-induced mitotic catastrophe in human prostate cancer cells.

Authors:  V Zvereff; J-C Wang; K Shun; J Lacoste; M Chevrette
Journal:  Br J Cancer       Date:  2007-09-11       Impact factor: 7.640
  6 in total

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