Literature DB >> 10907699

Effects of perineural capsaicin treatment on cardiopulmonary reflexes elicited by laryngeal instillations of capsaicin and distilled water in sevoflurane-anesthetized dogs.

T Mutoh1, A Kanamaru, K Kojima, R Nishimura, N Sasaki, H Tsubone.   

Abstract

The aim of this study was to determine the effect of perineural capsaicin (CAPS) treatment on cardiopulmonary reflexes elicited by topical laryngeal instillation of CAPS and distilled water (DW) in sevoflurane-anesthetized dogs. Cardiopulmonary reflexes elicited by CAPS (10 microg/ml, 10 ml) were attenuated by perineural CAPS treatment to the superior laryngeal nerves (SLNs) (P<0.05), whereas those by DW (10 ml) remained unaffected (P>0.05). The reflex responses to DW that remained even after the perineural CAPS treatment were eliminated by laryngeal anesthesia with lidocaine. These results suggest that cardiopulmonary reflexes from the laryngeal mucosa elicited by CAPS instillation can be blocked by perineural CAPS treatment to the SLNs, which may result from inhibition of the laryngeal CAPS-sensitive C-fiber afferents.

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Year:  2000        PMID： 10907699     DOI： 10.1292/jvms.62.665

Source DB:  PubMed          Journal:  J Vet Med Sci        ISSN： 0916-7250            Impact factor:   1.267


  8 in total

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Journal:  Am J Physiol Lung Cell Mol Physiol       Date:  2019-10-16       Impact factor: 5.464

2.  Prenatal nicotinic exposure prolongs superior laryngeal C-fiber-mediated apnea and bradycardia through enhancing neuronal TRPV1 expression and excitation.

Authors:  Xiuping Gao; Lei Zhao; Jianguo Zhuang; Na Zang; Fadi Xu
Journal:  FASEB J       Date:  2017-06-14       Impact factor: 5.191

3.  Interleukin-1β and interleukin-6 enhance thermal prolongation of the LCR in decerebrate piglets.

Authors:  Luxi Xia; Donald Bartlett; J C Leiter
Journal:  Respir Physiol Neurobiol       Date:  2016-05-12       Impact factor: 1.931

4.  Characterization of cardiovascular reflexes evoked by airway stimulation with allylisothiocyanate, capsaicin, and ATP in Sprague-Dawley rats.

Authors:  J S Hooper; S H Hadley; K F Morris; J W Breslin; J B Dean; T E Taylor-Clark
Journal:  J Appl Physiol (1985)       Date:  2015-12-30

5.  Central inhibition of initiation of swallowing by systemic administration of diazepam and baclofen in anaesthetized rats.

Authors:  Takanori Tsujimura; Shogo Sakai; Taku Suzuki; Izumi Ujihara; Kojun Tsuji; Jin Magara; Brendan J Canning; Makoto Inoue
Journal:  Am J Physiol Gastrointest Liver Physiol       Date:  2017-03-02       Impact factor: 4.052

6.  Serotonin in the solitary tract nucleus shortens the laryngeal chemoreflex in anaesthetized neonatal rats.

Authors:  William T Donnelly; Donald Bartlett; J C Leiter
Journal:  Exp Physiol       Date:  2016-06-12       Impact factor: 2.969

7.  Prenatal intermittent hypoxia sensitizes the laryngeal chemoreflex, blocks serotoninergic shortening of the reflex, and reduces 5-HT3 receptor binding in the NTS in anesthetized rat pups.

Authors:  William T Donnelly; Robin L Haynes; Kathryn G Commons; Drexel J Erickson; Chris M Panzini; Luxi Xia; Q Joyce Han; J C Leiter
Journal:  Exp Neurol       Date:  2019-12-27       Impact factor: 5.330

8.  Intralaryngeal application of ATP evokes apneic response mainly via acting on P2X3 (P2X2/3) receptors of the superior laryngeal nerve in postnatal rats.

Authors:  Jianguo Zhuang; Xiuping Gao; Wan Wei; Amir Pelleg; Fadi Xu
Journal:  J Appl Physiol (1985)       Date:  2021-07-29
  8 in total

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