| Literature DB >> 10906962 |
G Bleau1, F Massicotte, Y Merlen, C Boisvert.
Abstract
Mammals express genes coding for proteins that show significant similarity to chitinases of family 18 glycosyl hydrolases. These chitinase-like proteins have no chitinase activity due to changes in critical residues in the putative active center. One of these is oviductin, a high molecular weight glycoprotein most likely involved in fertilization and protection of the tubal epithelium owing to its mucin character. Another is YKL-40 (HCgp39) produced in association with tissue remodeling. Such proteins could have a general function in morphogenesis.Entities:
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Year: 1999 PMID： 10906962 DOI： 10.1007/978-3-0348-8757-1_15
Source DB: PubMed Journal: EXS ISSN： 1023-294X