Literature DB >> 10903952

Luxury accommodations: the expanding role of structural plasticity in protein-protein interactions.

E J Sundberg1, R A Mariuzza.   

Abstract

The recognition of multiple ligands at a single molecular surface is essential to many biological processes. Conformational flexibility has emerged as a compelling strategy for association at such convergent binding sites. Studies over the past few years have brought about a greater understanding of the role that protein plasticity might play in protein-protein interactions.

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Year:  2000        PMID： 10903952     DOI： 10.1016/s0969-2126(00)00167-2

Source DB:  PubMed          Journal:  Structure        ISSN： 0969-2126            Impact factor:   5.006


  16 in total

Review 1.  Multiple diverse ligands binding at a single protein site: a matter of pre-existing populations.

Authors:  Buyong Ma; Maxim Shatsky; Haim J Wolfson; Ruth Nussinov
Journal:  Protein Sci       Date:  2002-02       Impact factor: 6.725

2.  Plasticity in protein-peptide recognition: crystal structures of two different peptides bound to concanavalin A.

Authors:  D Jain; K J Kaur; D M Salunke
Journal:  Biophys J       Date:  2001-06       Impact factor: 4.033

3.  Structure and interactions of the carboxyl terminus of striated muscle alpha-tropomyosin: it is important to be flexible.

Authors:  Norma J Greenfield; Thomas Palm; Sarah E Hitchcock-DeGregori
Journal:  Biophys J       Date:  2002-11       Impact factor: 4.033

4.  Protein-protein interactions: structurally conserved residues distinguish between binding sites and exposed protein surfaces.

Authors:  Buyong Ma; Tal Elkayam; Haim Wolfson; Ruth Nussinov
Journal:  Proc Natl Acad Sci U S A       Date:  2003-05-01       Impact factor: 11.205

5.  Substrate-induced changes in protease active site conformation impact on subsequent reactions with substrates.

Authors:  Rong Pan; Image Image; Xue-Jing Zhang; Image Image Image; Zi-Jian Zhang; Image Image Image; Yuan Zhou; Image Image; Wei-Xi Tian; Image Image Image; Rong-Qiao He; Image Image Image
Journal:  J Biol Chem       Date:  2010-05-18       Impact factor: 5.157

6.  Specificity in molecular design: a physical framework for probing the determinants of binding specificity and promiscuity in a biological environment.

Authors:  Mala L Radhakrishnan; Bruce Tidor
Journal:  J Phys Chem B       Date:  2007-11-03       Impact factor: 2.991

7.  Antigen presentation subverted: Structure of the human cytomegalovirus protein US2 bound to the class I molecule HLA-A2.

Authors:  B E Gewurz; R Gaudet; D Tortorella; E W Wang; H L Ploegh; D C Wiley
Journal:  Proc Natl Acad Sci U S A       Date:  2001-06-05       Impact factor: 11.205

8.  Molecular basis of in vitro affinity maturation and functional evolution of a neutralizing anti-human GM-CSF antibody.

Authors:  Roy Eylenstein; Daniel Weinfurtner; Stefan Härtle; Ralf Strohner; Jark Böttcher; Martin Augustin; Ralf Ostendorp; Stefan Steidl
Journal:  MAbs       Date:  2015-09-25       Impact factor: 5.857

9.  A single intermolecular contact mediates intramolecular stabilization of both RNA and protein.

Authors:  Valerie Calabro; Matthew D Daugherty; Alan D Frankel
Journal:  Proc Natl Acad Sci U S A       Date:  2005-04-27       Impact factor: 11.205

10.  Binding site on human immunoglobulin G for the affinity ligand HWRGWV.

Authors:  Haiou Yang; Patrick V Gurgel; D Keith Williams; Benjamin G Bobay; John Cavanagh; David C Muddiman; Ruben G Carbonell
Journal:  J Mol Recognit       Date:  2010 May-Jun       Impact factor: 2.137
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