Literature DB >> 10903573

Maternal care, hippocampal synaptogenesis and cognitive development in rats.

D Liu1, J Diorio, J C Day, D D Francis, M J Meaney.   

Abstract

We report that variations in maternal care in the rat promote hippocampal synaptogenesis and spatial learning and memory through systems known to mediate experience-dependent neural development. Thus, the offspring of mothers that show high levels of pup licking and grooming and arched-back nursing showed increased expression of NMDA receptor subunit and brain-derived neurotrophic factor (BDNF) mRNA, increased cholinergic innervation of the hippocampus and enhanced spatial learning and memory. A cross-fostering study provided evidence for a direct relationship between maternal behavior and hippocampal development, although not all neonates were equally sensitive to variations in maternal care.

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Year:  2000        PMID： 10903573     DOI： 10.1038/77702

Source DB:  PubMed          Journal:  Nat Neurosci        ISSN： 1097-6256            Impact factor:   24.884


  264 in total

1.  Neonatal exposure to novel environment enhances hippocampal-dependent memory function during infancy and adulthood.

Authors:  A C Tang
Journal:  Learn Mem       Date:  2001 Sep-Oct       Impact factor: 2.460

2.  Naturally occurring variations in maternal behavior in the rat are associated with differences in estrogen-inducible central oxytocin receptors.

Authors:  F Champagne; J Diorio; S Sharma; M J Meaney
Journal:  Proc Natl Acad Sci U S A       Date:  2001-10-16       Impact factor: 11.205

3.  Corticostriatal-limbic gray matter morphology in adolescents with self-reported exposure to childhood maltreatment.

Authors:  Erin E Edmiston; Fei Wang; Carolyn M Mazure; Joanne Guiney; Rajita Sinha; Linda C Mayes; Hilary P Blumberg
Journal:  Arch Pediatr Adolesc Med       Date:  2011-12

4.  Early enriched environment promotes neonatal GABAergic neurotransmission and accelerates synapse maturation.

Authors:  Shan He; Jun Ma; Na Liu; Xiang Yu
Journal:  J Neurosci       Date:  2010-06-09       Impact factor: 6.167

5.  A limited access mouse model of prenatal alcohol exposure that produces long-lasting deficits in hippocampal-dependent learning and memory.

Authors:  Megan L Brady; Andrea M Allan; Kevin K Caldwell
Journal:  Alcohol Clin Exp Res       Date:  2011-09-20       Impact factor: 3.455

6.  Postnatal microbial colonization programs the hypothalamic-pituitary-adrenal system for stress response in mice.

Authors:  Nobuyuki Sudo; Yoichi Chida; Yuji Aiba; Junko Sonoda; Naomi Oyama; Xiao-Nian Yu; Chiharu Kubo; Yasuhiro Koga
Journal:  J Physiol       Date:  2004-05-07       Impact factor: 5.182

7.  Pharmacological activation of group-II metabotropic glutamate receptors corrects a schizophrenia-like phenotype induced by prenatal stress in mice.

Authors:  Francesco Matrisciano; Patricia Tueting; Stefania Maccari; Ferdinando Nicoletti; Alessandro Guidotti
Journal:  Neuropsychopharmacology       Date:  2011-11-16       Impact factor: 7.853

8.  Effects of brief stress exposure during early postnatal development in Balb/CByJ mice: II. Altered cortical morphology.

Authors:  C F Hohmann; N A Beard; P Kari-Kari; N Jarvis; Q Simmons
Journal:  Dev Psychobiol       Date:  2012-04-04       Impact factor: 3.038

9.  Prior parity positively regulates learning and memory in young and middle-aged rats.

Authors:  Erica Zimberknopf; Gilberto F Xavier; Craig H Kinsley; Luciano F Felicio
Journal:  Comp Med       Date:  2011-08       Impact factor: 0.982

10.  Early repeated maternal separation induces alterations of hippocampus reelin expression in rats.

Authors:  Jianlong Zhang; Lina Qin; Hu Zhao
Journal:  J Biosci       Date:  2013-03       Impact factor: 1.826
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