Literature DB >> 10903331

Novel treatments for osteoporosis.

E Canalis1.   

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Year:  2000        PMID: 10903331      PMCID: PMC314318          DOI: 10.1172/JCI10584

Source DB:  PubMed          Journal:  J Clin Invest        ISSN: 0021-9738            Impact factor:   14.808


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  23 in total

1.  Atp6i-deficient mice exhibit severe osteopetrosis due to loss of osteoclast-mediated extracellular acidification.

Authors:  Y P Li; W Chen; Y Liang; E Li; P Stashenko
Journal:  Nat Genet       Date:  1999-12       Impact factor: 38.330

2.  Sensitivity to vanadate and isoforms of subunits A and B distinguish the osteoclast proton pump from other vacuolar H+ ATPases.

Authors:  D Chatterjee; M Chakraborty; M Leit; L Neff; S Jamsa-Kellokumpu; R Fuchs; R Baron
Journal:  Proc Natl Acad Sci U S A       Date:  1992-07-15       Impact factor: 11.205

3.  The gene encoding the mouse homologue of the human osteoclast-specific 116-kDa V-ATPase subunit bears a deletion in osteosclerotic (oc/oc) mutants.

Authors:  J C Scimeca; A Franchi; C Trojani; H Parrinello; J Grosgeorge; C Robert; O Jaillon; C Poirier; P Gaudray; G F Carle
Journal:  Bone       Date:  2000-03       Impact factor: 4.398

4.  (2Z,4E)-5-(5,6-dichloro-2-indolyl)-2-methoxy-N-(1,2,2,6,6- pentamethylpiperidin-4-yl)-2,4-pentadienamide, a novel, potent and selective inhibitor of the osteoclast V-ATPase.

Authors:  G Nadler; M Morvan; I Delimoge; P Belfiore; A Zocchetti; I James; D Zembryki; E Lee-Rycakzewski; C Parini; E Consolandi; S Gagliardi; C Farina
Journal:  Bioorg Med Chem Lett       Date:  1998-12-15       Impact factor: 2.823

5.  Insulin-like growth factor I mediates selective anabolic effects of parathyroid hormone in bone cultures.

Authors:  E Canalis; M Centrella; W Burch; T L McCarthy
Journal:  J Clin Invest       Date:  1989-01       Impact factor: 14.808

6.  Insulin receptor substrate-1 in osteoblast is indispensable for maintaining bone turnover.

Authors:  N Ogata; D Chikazu; N Kubota; Y Terauchi; K Tobe; Y Azuma; T Ohta; T Kadowaki; K Nakamura; H Kawaguchi
Journal:  J Clin Invest       Date:  2000-04       Impact factor: 14.808

7.  A selective inhibitor of the osteoclastic V-H(+)-ATPase prevents bone loss in both thyroparathyroidectomized and ovariectomized rats.

Authors:  L Visentin; R A Dodds; M Valente; P Misiano; J N Bradbeer; S Oneta; X Liang; M Gowen; C Farina
Journal:  J Clin Invest       Date:  2000-07       Impact factor: 14.808

8.  Antagonizing the parathyroid calcium receptor stimulates parathyroid hormone secretion and bone formation in osteopenic rats.

Authors:  M Gowen; G B Stroup; R A Dodds; I E James; B J Votta; B R Smith; P K Bhatnagar; A M Lago; J F Callahan; E G DelMar; M A Miller; E F Nemeth; J Fox
Journal:  J Clin Invest       Date:  2000-06       Impact factor: 14.808

9.  Cloning and characterization of an extracellular Ca(2+)-sensing receptor from bovine parathyroid.

Authors:  E M Brown; G Gamba; D Riccardi; M Lombardi; R Butters; O Kifor; A Sun; M A Hediger; J Lytton; S C Hebert
Journal:  Nature       Date:  1993-12-09       Impact factor: 49.962

10.  Molecular cloning and characterization of a putative novel human osteoclast-specific 116-kDa vacuolar proton pump subunit.

Authors:  Y P Li; W Chen; P Stashenko
Journal:  Biochem Biophys Res Commun       Date:  1996-01-26       Impact factor: 3.575

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  3 in total

1.  Methionine down-regulates TLR4/MyD88/NF-κB signalling in osteoclast precursors to reduce bone loss during osteoporosis.

Authors:  V Vijayan; M Khandelwal; K Manglani; S Gupta; A Surolia
Journal:  Br J Pharmacol       Date:  2014-01       Impact factor: 8.739

Review 2.  New understanding and treatments for osteoporosis.

Authors:  G Mazziotti; J Bilezikian; E Canalis; D Cocchi; A Giustina
Journal:  Endocrine       Date:  2012-02       Impact factor: 3.633

3.  Calcium-sensing receptor (CaSR) promotes development of bone metastasis in renal cell carcinoma.

Authors:  Sebastian Frees; Ines Breuksch; Tobias Haber; Heide-Katharina Bauer; Claudia Chavez-Munoz; Peter Raven; Igor Moskalev; Ninadh D Costa; Zheng Tan; Mads Daugaard; Joachim W Thüroff; Axel Haferkamp; Dirk Prawitt; Alan So; Walburgis Brenner
Journal:  Oncotarget       Date:  2018-03-02
  3 in total

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