Literature DB >> 10902178

Algorithms for inferring qualitative models of biological networks.

T Akutsu1, S Miyano, S Kuhara.   

Abstract

Modeling genetic networks and metabolic networks is an important topic in bioinformatics. We propose a qualitative network model which is a combination of the Boolean network and qualitative reasoning, where qualitative reasoning is a kind of reasoning method well-studied in Artificial Intelligence. We also present algorithms for inferring qualitative networks from time series data and an algorithm for inferring S-systems (synergistic and saturable systems) from time series data, where S-systems are based on a particular kind of nonlinear differential equation and have been applied to the analysis of various biological systems.

Mesh:

Year:  2000        PMID: 10902178     DOI: 10.1142/9789814447331_0028

Source DB:  PubMed          Journal:  Pac Symp Biocomput        ISSN: 2335-6928


  13 in total

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