| Literature DB >> 10902178 |
T Akutsu1, S Miyano, S Kuhara.
Abstract
Modeling genetic networks and metabolic networks is an important topic in bioinformatics. We propose a qualitative network model which is a combination of the Boolean network and qualitative reasoning, where qualitative reasoning is a kind of reasoning method well-studied in Artificial Intelligence. We also present algorithms for inferring qualitative networks from time series data and an algorithm for inferring S-systems (synergistic and saturable systems) from time series data, where S-systems are based on a particular kind of nonlinear differential equation and have been applied to the analysis of various biological systems.Mesh:
Year: 2000 PMID: 10902178 DOI: 10.1142/9789814447331_0028
Source DB: PubMed Journal: Pac Symp Biocomput ISSN: 2335-6928