Literature DB >> 10901432

Lipid analog with 2-nitrophenol trigger designed for liposome fusion at physiological pH.

S N Shah1, T Tomohiro, Y Ogawa, M Kodaka, H Okuno.   

Abstract

A novel lipid analog with two long alkyl (C16) chains, an aspartate skeleton, a connecting alkyl (C8) chain, and 2-nitrophenol trigger group is synthesized by an efficient synthetic route, which can induce liposome fusion at physiological pH.

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Year:  2000        PMID： 10901432     DOI： 10.1007/s11745-000-0574-2

Source DB:  PubMed          Journal:  Lipids        ISSN： 0024-4201            Impact factor:   1.880


  8 in total

1.  Inhibition of Bax channel-forming activity by Bcl-2.

Authors:  B Antonsson; F Conti; A Ciavatta; S Montessuit; S Lewis; I Martinou; L Bernasconi; A Bernard; J J Mermod; G Mazzei; K Maundrell; F Gambale; R Sadoul; J C Martinou
Journal:  Science       Date:  1997-07-18       Impact factor: 47.728

2.  Highly efficient DNA delivery mediated by pH-sensitive immunoliposomes.

Authors:  C Y Wang; L Huang
Journal:  Biochemistry       Date:  1989-11-28       Impact factor: 3.162

3.  pH-sensitive immunoliposomes mediate target-cell-specific delivery and controlled expression of a foreign gene in mouse.

Authors:  C Y Wang; L Huang
Journal:  Proc Natl Acad Sci U S A       Date:  1987-11       Impact factor: 11.205

4.  Preparation of functional liposomes with peptide ligands and their binding to cell membranes.

Authors:  N Yagi; Y Ogawa; M Kodaka; T Okada; T Tomohiro; T Konakahara; H Okuno
Journal:  Lipids       Date:  2000-06       Impact factor: 1.880

5.  Synthesis of a novel lipopeptide with alpha-melanocyte-stimulating hormone peptide ligand and its effect on liposome stability.

Authors:  Y Ogawa; H Kawahara; N Yagi; M Kodaka; T Tomohiro; T Okada; T Konakahara; H Okuno
Journal:  Lipids       Date:  1999-04       Impact factor: 1.880

6.  Oligonucleotides encapsulated in pH sensitive liposomes are efficient toward Friend retrovirus.

Authors:  C Ropert; M Lavignon; C Dubernet; P Couvreur; C Malvy
Journal:  Biochem Biophys Res Commun       Date:  1992-03-16       Impact factor: 3.575

7.  pH-dependent interaction of amphiphilic polypeptide poly(Lys-Aib-Leu-Aib) with lipid bilayer membrane.

Authors:  K Kono; S Kimura; Y Imanishi
Journal:  Biochemistry       Date:  1990-04-17       Impact factor: 3.162

8.  Fusion activity of an amphiphilic polypeptide having acidic amino acid residues: generation of fusion activity by alpha-helix formation and charge neutralization.

Authors:  K Kono; H Nishii; T Takagishi
Journal:  Biochim Biophys Acta       Date:  1993-06-24
  8 in total

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