| Literature DB >> 10899896 |
Abstract
Pertactin is an outer membrane protein expressed by Bordetella pertussis, Bordetella parapertussis, and Bordetella bronchiseptica that induces protective immunity to Bordetella infections. The immunodominant and immunoprotective epitopes of pertactin include two repeated regions, I and II. Comparison of these two repeated regions showed that B. parapertussis pertactin is invariant, whereas B. pertussis pertactin varies mostly in region I and B. bronchiseptica pertactin varies in both repeated regions I and II, but mostly in region II. These differences may result from specific characteristics of these Bordetella species.Entities:
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Year: 2000 PMID: 10899896 PMCID: PMC98445 DOI: 10.1128/IAI.68.8.4815-4817.2000
Source DB: PubMed Journal: Infect Immun ISSN: 0019-9567 Impact factor: 3.441