Literature DB >> 10899886

Characterization of the Streptococcus mutans pyruvate formate-lyase (PFL)-activating enzyme gene by complementary reconstitution of the In vitro PFL-reactivating system.

Y Yamamoto1, Y Sato, S Takahashi-Abbe, N Takahashi, H Kizaki.   

Abstract

The act gene was identified and an act mutant as well as the pfl mutant was constructed in Streptococcus mutans. Pyruvate formate-lyase (PFL) activity was regenerated with the mixture of the respective cell extracts from these mutants by complementary reconstitution of the in vitro reactivating system. The S. mutans act gene encoded the sole enzyme able to activate the PFL protein in this organism.

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Year:  2000        PMID: 10899886      PMCID: PMC98435          DOI: 10.1128/IAI.68.8.4773-4777.2000

Source DB:  PubMed          Journal:  Infect Immun        ISSN: 0019-9567            Impact factor:   3.441


  28 in total

1.  Physical and genetic map of Streptococcus mutans GS-5 and localization of five rRNA operons.

Authors:  M G Cappiello; M J Hantman; F M Zuccon; F Peruzzi; M Amjad; P J Piggot; L Daneo-Moore
Journal:  Oral Microbiol Immunol       Date:  1999-08

2.  Primary structures of Escherichia coli pyruvate formate-lyase and pyruvate-formate-lyase-activating enzyme deduced from the DNA nucleotide sequences.

Authors:  W Rödel; W Plaga; R Frank; J Knappe
Journal:  Eur J Biochem       Date:  1988-10-15

Review 3.  Role of Streptococcus mutans in human dental decay.

Authors:  W J Loesche
Journal:  Microbiol Rev       Date:  1986-12

4.  Post-translational activation introduces a free radical into pyruvate formate-lyase.

Authors:  J Knappe; F A Neugebauer; H P Blaschkowski; M Gänzler
Journal:  Proc Natl Acad Sci U S A       Date:  1984-03       Impact factor: 11.205

5.  Regulation of lactate dehydrogenase and change of fermentation products in streptococci.

Authors:  T Yamada; J Carlsson
Journal:  J Bacteriol       Date:  1975-10       Impact factor: 3.490

6.  Purification of pyruvate formate-lyase from Streptococcus mutans and its regulatory properties.

Authors:  S Takahashi; K Abbe; T Yamada
Journal:  J Bacteriol       Date:  1982-03       Impact factor: 3.490

7.  Oxygen sensitivity of sugar metabolism and interconversion of pyruvate formate-lyase in intact cells of Streptococcus mutans and Streptococcus sanguis.

Authors:  N Takahashi; K Abbe; S Takahashi-Abbe; T Yamada
Journal:  Infect Immun       Date:  1987-03       Impact factor: 3.441

8.  Involvement of oxygen-sensitive pyruvate formate-lyase in mixed-acid fermentation by Streptococcus mutans under strictly anaerobic conditions.

Authors:  K Abbe; S Takahashi; T Yamada
Journal:  J Bacteriol       Date:  1982-10       Impact factor: 3.490

9.  Effects of oxygen on pyruvate formate-lyase in situ and sugar metabolism of Streptococcus mutans and Streptococcus sanguis.

Authors:  T Yamada; S Takahashi-Abbe; K Abbe
Journal:  Infect Immun       Date:  1985-01       Impact factor: 3.441

10.  A dehydroalanyl residue can capture the 5'-deoxyadenosyl radical generated from S-adenosylmethionine by pyruvate formate-lyase-activating enzyme.

Authors:  A F Wagner; J Demand; G Schilling; T Pils; J Knappe
Journal:  Biochem Biophys Res Commun       Date:  1999-01-19       Impact factor: 3.575

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  5 in total

1.  Transcriptional repressor Rex is involved in regulation of oxidative stress response and biofilm formation by Streptococcus mutans.

Authors:  Jacob P Bitoun; Anne H Nguyen; Yuwei Fan; Robert A Burne; Zezhang T Wen
Journal:  FEMS Microbiol Lett       Date:  2011-05-13       Impact factor: 2.742

2.  Pyruvate formate lyase is required for pneumococcal fermentative metabolism and virulence.

Authors:  Hasan Yesilkaya; Francesca Spissu; Sandra M Carvalho; Vanessa S Terra; Karen A Homer; Rachel Benisty; Nurith Porat; Ana R Neves; Peter W Andrew
Journal:  Infect Immun       Date:  2009-09-14       Impact factor: 3.441

3.  Molecular characterization and expression of pyruvate formate-lyase-activating enzyme in a ruminal bacterium, Streptococcus bovis.

Authors:  Narito Asanuma; Tsuneo Hino
Journal:  Appl Environ Microbiol       Date:  2002-07       Impact factor: 4.792

4.  The redox-sensing regulator Rex modulates central carbon metabolism, stress tolerance response and biofilm formation by Streptococcus mutans.

Authors:  Jacob P Bitoun; Sumei Liao; Xin Yao; Gary G Xie; Zezhang T Wen
Journal:  PLoS One       Date:  2012-09-13       Impact factor: 3.240

5.  Saliva microbiota carry caries-specific functional gene signatures.

Authors:  Fang Yang; Kang Ning; Xingzhi Chang; Xiao Yuan; Qichao Tu; Tong Yuan; Ye Deng; Christopher L Hemme; Joy Van Nostrand; Xinping Cui; Zhili He; Zhenggang Chen; Dawei Guo; Jiangbo Yu; Yue Zhang; Jizhong Zhou; Jian Xu
Journal:  PLoS One       Date:  2014-02-12       Impact factor: 3.240

  5 in total

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