Literature DB >> 10899814

A SNPshot: pharmacogenetics and the future of drug therapy.

D R Pfost1, M T Boyce-Jacino, D M Grant.   

Abstract

Pharmacogenetics holds great promise for the optimization of new drug development and the individualization of clinical therapeutics in the 21st century. In this brief review, we trace the historical roots of pharmacogenetics, discuss its rapidly evolving processes and paradigms, and look towards future applications of pharmacogenetics in enhancing the efficiency of the drug development pipeline and in improving patient care.

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Year:  2000        PMID: 10899814     DOI: 10.1016/s0167-7799(00)01463-3

Source DB:  PubMed          Journal:  Trends Biotechnol        ISSN: 0167-7799            Impact factor:   19.536


  5 in total

1.  Characterisation of single nucleotide polymorphisms in sugarcane ESTs.

Authors:  Giovanni M Cordeiro; Frances Eliott; C Lynne McIntyre; Rosanne E Casu; Robert J Henry
Journal:  Theor Appl Genet       Date:  2006-05-20       Impact factor: 5.699

2.  A rapid screening method for a single nucleotide polymorphism (SNP) in the human MOR gene.

Authors:  S Grösch; E Niederberger; J Lötsch; C Skarke; G Geisslinger
Journal:  Br J Clin Pharmacol       Date:  2001-12       Impact factor: 4.335

3.  The role of the ADRA2A C1291G genetic polymorphism in response to dexmedetomidine on patients undergoing coronary artery surgery.

Authors:  Seyhan Yağar; Soner Yavaş; Bensu Karahalil
Journal:  Mol Biol Rep       Date:  2010-11-23       Impact factor: 2.316

Review 4.  Clinical significance of the cytochrome P450 2C19 genetic polymorphism.

Authors:  Zeruesenay Desta; Xiaojiong Zhao; Jae-Gook Shin; David A Flockhart
Journal:  Clin Pharmacokinet       Date:  2002       Impact factor: 6.447

5.  Text mining facilitates database curation - extraction of mutation-disease associations from Bio-medical literature.

Authors:  Komandur Elayavilli Ravikumar; Kavishwar B Wagholikar; Dingcheng Li; Jean-Pierre Kocher; Hongfang Liu
Journal:  BMC Bioinformatics       Date:  2015-06-06       Impact factor: 3.169

  5 in total

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