Literature DB >> 10899539

A practical large-scale synthesis of 17alpha-acetoxy-11beta-(4-N, N-dimethylaminophenyl)-19-norpregna-4,9-diene-3,20-dione (CDB-2914).

P N Rao1, C K Acosta, M L Bahr, J E Burdett, J W Cessac, P A Morrison, H K Kim.   

Abstract

A new practical synthesis of 17alpha-acetoxy-11beta-(4-N, N-dimethylaminophenyl)-19-norpregna-4,9-diene-3,20-dione (CDB-2914) is described. The synthesis gives easily isolable solids at all steps and is amenable to large-scale process.

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Year:  2000        PMID: 10899539     DOI: 10.1016/s0039-128x(00)00100-8

Source DB:  PubMed          Journal:  Steroids        ISSN: 0039-128X            Impact factor:   2.668


  1 in total

1.  Novel RU486 (mifepristone) analogues with increased activity against Venezuelan Equine Encephalitis Virus but reduced progesterone receptor antagonistic activity.

Authors:  Aaron DeBono; David R Thomas; Lindsay Lundberg; Chelsea Pinkham; Ying Cao; J Dinny Graham; Christine L Clarke; Kylie M Wagstaff; Sharon Shechter; Kylene Kehn-Hall; David A Jans
Journal:  Sci Rep       Date:  2019-02-22       Impact factor: 4.379

  1 in total

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