Literature DB >> 10899437

Structure of tau protein and assembly into paired helical filaments.

P Friedhoff1, M von Bergen, E M Mandelkow, E Mandelkow.   

Abstract

Over the past few years the systematic investigation of paired helical filament assembly from tau protein in vitro has become feasible. We review our current understanding of the structure and conformations of tau protein and how this affects tau's assembly into the pathological paired helical filaments in Alzheimer's disease.

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Year:  2000        PMID: 10899437     DOI: 10.1016/s0925-4439(00)00038-7

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN: 0006-3002


  36 in total

1.  Inhibition of glycogen synthase kinase-3 by lithium correlates with reduced tauopathy and degeneration in vivo.

Authors:  Wendy Noble; Emmanuel Planel; Cindy Zehr; Vicki Olm; Jordana Meyerson; Farhana Suleman; Kate Gaynor; Lili Wang; John LaFrancois; Boris Feinstein; Mark Burns; Pavan Krishnamurthy; Yi Wen; Ratan Bhat; Jada Lewis; Dennis Dickson; Karen Duff
Journal:  Proc Natl Acad Sci U S A       Date:  2005-05-02       Impact factor: 11.205

2.  The amyloid-beta precursor protein is phosphorylated via distinct pathways during differentiation, mitosis, stress, and degeneration.

Authors:  Zoia Muresan; Virgil Muresan
Journal:  Mol Biol Cell       Date:  2007-07-18       Impact factor: 4.138

Review 3.  Axonal transport, tau protein, and neurodegeneration in Alzheimer's disease.

Authors:  Dick Terwel; Ilse Dewachter; Fred Van Leuven
Journal:  Neuromolecular Med       Date:  2002       Impact factor: 3.843

4.  Secondary nucleating sequences affect kinetics and thermodynamics of tau aggregation.

Authors:  Christopher L Moore; Michael H Huang; Shauna A Robbennolt; Kellen R Voss; Benjamin Combs; T Chris Gamblin; Warren J Goux
Journal:  Biochemistry       Date:  2011-11-29       Impact factor: 3.162

5.  Hsp70 alters tau function and aggregation in an isoform specific manner.

Authors:  Kellen Voss; Benjamin Combs; Kristina R Patterson; Lester I Binder; T Chris Gamblin
Journal:  Biochemistry       Date:  2012-01-23       Impact factor: 3.162

Review 6.  Targeting Abeta and tau in Alzheimer's disease, an early interim report.

Authors:  Todd E Golde; Leonard Petrucelli; Jada Lewis
Journal:  Exp Neurol       Date:  2009-08-27       Impact factor: 5.330

7.  Concentration-dependent effects of proteasomal inhibition on tau processing in a cellular model of tauopathy.

Authors:  Tadanori Hamano; Tania F Gendron; Li-Wen Ko; Shu-Hui Yen
Journal:  Int J Clin Exp Pathol       Date:  2009-06-15

8.  Functional anthology of intrinsic disorder. 2. Cellular components, domains, technical terms, developmental processes, and coding sequence diversities correlated with long disordered regions.

Authors:  Slobodan Vucetic; Hongbo Xie; Lilia M Iakoucheva; Christopher J Oldfield; A Keith Dunker; Zoran Obradovic; Vladimir N Uversky
Journal:  J Proteome Res       Date:  2007-03-29       Impact factor: 4.466

9.  Low micromolar zinc accelerates the fibrillization of human tau via bridging of Cys-291 and Cys-322.

Authors:  Zhong-Ying Mo; Ying-Zhu Zhu; Hai-Li Zhu; Jun-Bao Fan; Jie Chen; Yi Liang
Journal:  J Biol Chem       Date:  2009-10-13       Impact factor: 5.157

Review 10.  Apolipoprotein E: diversity of cellular origins, structural and biophysical properties, and effects in Alzheimer's disease.

Authors:  Yadong Huang; Karl H Weisgraber; Lennart Mucke; Robert W Mahley
Journal:  J Mol Neurosci       Date:  2004       Impact factor: 3.444

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