Literature DB >> 10899028

The role of CD4(+) T helper cells in the cytotoxic T lymphocyte response to HIV-1.

M Altfeld1, E S Rosenberg.   

Abstract

Virus-specific CD4(+) T cell help and CD8(+) cytotoxic T cell (CTL) responses are critical for the maintenance of effective immunity in chronic viral infections. HIV-1 infection presents a unique situation in which HIV-1-specific T helper cell responses are characteristically impaired and virus-specific CTLs wane over time as disease progresses; a relationship exists between T cell help and CTL responses in HIV-1 infection.

Entities:  

Mesh：

Year:  2000        PMID： 10899028     DOI： 10.1016/s0952-7915(00)00103-5

Source DB:  PubMed          Journal:  Curr Opin Immunol        ISSN： 0952-7915            Impact factor:   7.486


  39 in total

Review 1.  Memory CD8 T-cell differentiation during viral infection.

Authors:  E John Wherry; Rafi Ahmed
Journal:  J Virol       Date:  2004-06       Impact factor: 5.103

2.  HIV controllers with HLA-DRB1*13 and HLA-DQB1*06 alleles have strong, polyfunctional mucosal CD4+ T-cell responses.

Authors:  April L Ferre; Peter W Hunt; Delandy H McConnell; Megan M Morris; Juan C Garcia; Richard B Pollard; Hal F Yee; Jeffrey N Martin; Steven G Deeks; Barbara L Shacklett
Journal:  J Virol       Date:  2010-08-18       Impact factor: 5.103

3.  DNA/Ad5 vaccination with SIV epitopes induced epitope-specific CD4⁺ T cells, but few subdominant epitope-specific CD8⁺ T cells.

Authors:  Lara Vojnov; Alexander T Bean; Eric J Peterson; Maria J Chiuchiolo; Jonah B Sacha; Ferencz S Denes; Matyas Sandor; Deborah H Fuller; James T Fuller; Christopher L Parks; Adrian B McDermott; Nancy A Wilson; David I Watkins
Journal:  Vaccine       Date:  2011-08-10       Impact factor: 3.641

4.  Distinct kinetics of Gag-specific CD4+ and CD8+ T cell responses during acute HIV-1 infection.

Authors:  Catherine Riou; Vitaly V Ganusov; Suzanne Campion; Mandla Mlotshwa; Michael K P Liu; Victoria E Whale; Nilu Goonetilleke; Persephone Borrow; Guido Ferrari; Michael R Betts; Barton F Haynes; Andrew J McMichael; Clive M Gray
Journal:  J Immunol       Date:  2012-01-27       Impact factor: 5.422

5.  HIV-1 fusion peptide targets the TCR and inhibits antigen-specific T cell activation.

Authors:  Francisco J Quintana; Doron Gerber; Sally C Kent; Irun R Cohen; Yechiel Shai
Journal:  J Clin Invest       Date:  2005-07-07       Impact factor: 14.808

6.  Characterization of Gag and Nef-specific ELISpot-based CTL responses in HIV-1 infected Indian individuals.

Authors:  Sanjay Mendiratta; Madhu Vajpayee; Uma Malhotra; Shweta Kaushik; Lalit Dar; Kamalika Mojumdar; Neeraj Kumar Chauhan; Vishnubhatla Sreenivas
Journal:  Med Microbiol Immunol       Date:  2008-11-05       Impact factor: 3.402

7.  Consistent patterns in the development and immunodominance of human immunodeficiency virus type 1 (HIV-1)-specific CD8+ T-cell responses following acute HIV-1 infection.

Authors:  Xu G Yu; Marylyn M Addo; Eric S Rosenberg; William R Rodriguez; Paul K Lee; Cecily A Fitzpatrick; Mary N Johnston; Daryld Strick; Philip J R Goulder; Bruce D Walker; Marcus Altfeld
Journal:  J Virol       Date:  2002-09       Impact factor: 5.103

8.  The major histocompatibility complex class II alleles Mamu-DRB1*1003 and -DRB1*0306 are enriched in a cohort of simian immunodeficiency virus-infected rhesus macaque elite controllers.

Authors:  Juan P Giraldo-Vela; Richard Rudersdorf; Chungwon Chung; Ying Qi; Lyle T Wallace; Benjamin Bimber; Gretta J Borchardt; Debra L Fisk; Chrystal E Glidden; John T Loffredo; Shari M Piaskowski; Jessica R Furlott; Juan P Morales-Martinez; Nancy A Wilson; William M Rehrauer; Jeffrey D Lifson; Mary Carrington; David I Watkins
Journal:  J Virol       Date:  2007-11-07       Impact factor: 5.103

9.  HIV-1-suppressive factors are secreted by CD4+ T cells during primary immune responses.

Authors:  Sayed F Abdelwahab; Fiorenza Cocchi; Kenneth C Bagley; Roberta Kamin-Lewis; Robert C Gallo; Anthony DeVico; George K Lewis
Journal:  Proc Natl Acad Sci U S A       Date:  2003-12-01       Impact factor: 11.205

10.  Design and preclinical development of a recombinant protein and DNA plasmid mixed format vaccine to deliver HIV-derived T-lymphocyte epitopes.

Authors:  Leslie E Walker; Lo Vang; Xuefei Shen; Brian D Livingston; Penny Post; Alessandro Sette; C Steven Godin; Mark J Newman
Journal:  Vaccine       Date:  2009-09-26       Impact factor: 3.641
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