Literature DB >> 10898996

ER stress response: getting the UPR hand on misfolded proteins.

R Y Hampton1.   

Abstract

Unfolded proteins are constantly delivered to the ER lumen, where they must be removed by folding or degradation. Recent studies show that the 'unfolded protein response' controls essentially all aspects of ER function, coordinating these two fates for misfolded proteins in a process necessary for normal cell life.

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Year:  2000        PMID： 10898996     DOI： 10.1016/s0960-9822(00)00583-2

Source DB:  PubMed          Journal:  Curr Biol        ISSN： 0960-9822            Impact factor:   10.834


  71 in total

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