[Beta-2 microglobulinuria in children with vesico-ureteral reflux and recurrent urinary tract infections].

Recurrent urinary tract infections in children with vesico-ureteral reflux are the one of risk factors in the process of reflux nephropathy. One of markers of early kidney parenchyma damage is beta 2-microglobulin. The aim of the study was to evaluate the value of beta 2-microglobulin excretion in urine and its serum levels in children with vesico-ureteral reflux and recurrent urinary tract infections. It was found that abnormal urinary excretion of beta 2-microglobulin and its serum levels of proceeded post-inflammatory changes in kidney parenchyma observed in imaging examinations of urinary tract and impared parameters of renal function in biochemical analyses.