[Metabolic disorders in children with urolithiasis].

Nephrolithiasis is a common disease of multifactorial ethiopatogenesis. The majority of stone formers has disturbances in the metabolism and excretion of stone constituents, promotors or inhibitors of crystallization. The aim of our study was to evaluate metabolic disturbances in children with nephrolithiasis in the early stages of the disease. Cases with severe urinary obstruction, infection and glomerular filtration decrease were excluded. Daily calcium, uric acid, oxalate, phosphate, sodium, potassium, chloride, citrate, and magnesium excretion was examined in 27 children (12 M, 15 F, mean age--10.4 +/- 3.9 y). Hypercalciuria (10 cases) and hiperurykosuria (8 cases) were most often found in the studied group. We concluded that early diagnosis of metabolic background of stone formation (promotors and inhibitors) enables to apply proper preventive measures.