| Literature DB >> 10894223 |
J C Antoine1, L Cinotti, C Tilikete, F Bouhour, J P Camdessanché, C Confavreux, A Vighetto, V Renault-Mannel, D Michel, J Honnorat.
Abstract
The diagnosis of cancer is often difficult in patients with paraneoplastic neurological syndrome and anti-Hu antibodies. Fluorodeoxyglucose 18 positron emission tomography scanning is a highly sensitive and specific method to detect lung tumors. We investigated 15 patients with paraneoplastic neurological syndrome and anti-Hu antibodies. Radiological methods led to the diagnosis of cancer in 12 patients, and test results were negative in 3. Whole-body [18F]fluorodeoxyglucose positron emission tomography showed abnormal uptake in the mediastinum in these 3 patients in accordance with the expected location of the malignancy.Entities:
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Year: 2000 PMID： 10894223
Source DB: PubMed Journal: Ann Neurol ISSN： 0364-5134 Impact factor: 10.422