| Literature DB >> 10893519 |
M K Sammi1, J W Pan, F W Telang, D Schuhlein, P E Molina, N D Volkow, C S Springer, H P Hetherington.
Abstract
Previous MRS measurements of ethanol in human brain have yielded a range of transverse relaxation times for ethanol methyl resonance at 1.5 T (200-380 ms). To determine the T(2) of the methyl proton resonance of ethanol in human brain, 8 x 8 spectroscopic images were acquired at 16 different TE values. A frequency-selective refocusing pulse was used to suppress J-modulation of the ethanol triplet, permitting nonintegral multiples of 1/J to be used for TE values. The measured T(2) values for the methyl resonances of ethanol, creatine, and N-acetyl aspartate in mixed tissues were 82 +/- 12, 148 +/- 20, and 227 +/- 25 ms, respectively. Regression analysis of the measured T(2) as a function of gray matter content indicates a shorter T(2) value for ethanol in pure white matter compared to that in pure gray matter. Magn Reson Med 44:35-40, 2000. Copyright 2000 Wiley-Liss, Inc.Entities:
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Year: 2000 PMID： 10893519 DOI： 10.1002/1522-2594(200007)44:1<35::aid-mrm7>3.0.co;2-g
Source DB: PubMed Journal: Magn Reson Med ISSN： 0740-3194 Impact factor: 4.668