| Literature DB >> 10892600 |
T Perez-Ruiz1, C Martínez-Lozano, A Sanz, E Bravo.
Abstract
A sensitive and rapid capillary electrophoretic method combined with laser-induced fluorescence detection has been developed for the determination of ambroxol. Samples were derivatized with 5 x 10(-4) M fluorescein isothiocyanate. A linear relationship between concentration and peak area was obtained in the concentration range 0.008-42 microg ml(-1) with a correlation coefficient of 0.9999. The applicability of the method to serum and urine samples was demonstrated. The method is also useful for the determination of ambroxol in pharmaceutical preparations.Entities:
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Year: 2000 PMID： 10892600 DOI： 10.1016/s0378-4347(00)00150-x
Source DB: PubMed Journal: J Chromatogr B Biomed Sci Appl ISSN： 1387-2273