Literature DB >> 10891918

Response of leptomeningeal metastases from breast cancer to hormonal therapy.

W Boogerd1, L D Dorresteijn, J J van Der Sande, G C de Gast, P F Bruning.   

Abstract

Intraventricular chemotherapy with radiotherapy is the standard treatment of leptomeningeal metastasis (LM) from breast cancer; this treatment increases median survival only to about 3 months and is frequently complicated by serious side effects. The authors describe two patients with LM from breast cancer who were treated with hormonal therapy, which provided a neurologic response of at least 12 months and a survival of 14+ and 19 months. Hormonal therapy can be effective and nontoxic for patients with LM from breast cancer.

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Year:  2000        PMID： 10891918     DOI： 10.1212/wnl.55.1.117

Source DB:  PubMed          Journal:  Neurology        ISSN： 0028-3878            Impact factor:   9.910


  20 in total

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