Y G Maas1, M Mirmiran, A A Hart, J G Koppe, R L Ariagno, H Spekreijse. 1. Departments of Neonatology, Clinical Epidemiology and Biostatistics, and Visual System Analysis, Academical Medical Center, University of Amsterdam, The Netherlands.
Abstract
BACKGROUND: There is a need to identify, as early as possible, infants who are at risk for long-term neurological morbidity. METHODS: To predict neurodevelopment outcome of preterm infants <30 weeks' gestation in a population of 100 infants, we used several neonatal and neurobehavioral tests, including cranial ultrasonography, the Prechtl neurological test, quality of spontaneous general movements, and quality of sleep-wake organization. RESULTS: The Prechtl test at corrected term age and findings on cranial sonograms both had high specificity, but the Prechtl test had better overall positive predictive power for normal neurological and developmental outcomes at 2 years' corrected age. Developmental changes in sleep and the amount of indeterminate sleep did not correlate with outcome. Scoring general movement quality did not predict outcome and did not augment the positive predictive power of the Prechtl test. CONCLUSIONS: The Prechtl test at corrected term age (independent of the other tests) is the best positive predictor of normal neurological outcome and Bayley test results at 2 years' corrected age.
BACKGROUND: There is a need to identify, as early as possible, infants who are at risk for long-term neurological morbidity. METHODS: To predict neurodevelopment outcome of preterm infants <30 weeks' gestation in a population of 100 infants, we used several neonatal and neurobehavioral tests, including cranial ultrasonography, the Prechtl neurological test, quality of spontaneous general movements, and quality of sleep-wake organization. RESULTS: The Prechtl test at corrected term age and findings on cranial sonograms both had high specificity, but the Prechtl test had better overall positive predictive power for normal neurological and developmental outcomes at 2 years' corrected age. Developmental changes in sleep and the amount of indeterminate sleep did not correlate with outcome. Scoring general movement quality did not predict outcome and did not augment the positive predictive power of the Prechtl test. CONCLUSIONS: The Prechtl test at corrected term age (independent of the other tests) is the best positive predictor of normal neurological outcome and Bayley test results at 2 years' corrected age.
Authors: Pilar Medina-Alva; Kevin R Duque; Alonso Zea-Vera; Sicilia Bellomo; César Cárcamo; Daniel Guillen-Pinto; Maria Rivas; Alfredo Tori; Jaime Zegarra; Luis Cam; Anne Castañeda; Aasith Villavicencio; Theresa J Ochoa Journal: Early Hum Dev Date: 2019-02-08 Impact factor: 2.079
Authors: Isabel U Huf; Emmah Baque; Paul B Colditz; Mark D Chatfield; Robert S Ware; Roslyn N Boyd; Joanne M George Journal: Pediatr Res Date: 2022-09-23 Impact factor: 3.953
Authors: Diego Gazzolo; Francesca Pluchinotta; Moataza Bashir; Hanna Aboulgar; Hala Mufeed Said; Iskander Iman; Giorgio Ivani; Alessandra Conio; Lucia Gabriella Tina; Francesco Nigro; Giovanni Li Volti; Fabio Galvano; Fabrizio Michetti; Romolo Di Iorio; Emanuela Marinoni; Luc J Zimmermann; Antonio D W Gavilanes; Hans J S Vles; Maria Kornacka; Darek Gruszfeld; Rosanna Frulio; Renata Sacchi; Sabina Ciotti; Francesco M Risso; Andrea Sannia; Pasquale Florio Journal: PLoS One Date: 2015-01-08 Impact factor: 3.240