Literature DB >> 10891376

Structural study of the exopolysaccharide produced by a clinical isolate of Burkholderia cepacia.

P Cescutti1, M Bosco, F Picotti, G Impallomeni, J H Leitão, J A Richau, I Sá-Correia.   

Abstract

The primary structure of the exopolysaccharide produced by a clinical isolate of the bacterium Burkholderia cepacia was studied by means of methylation analysis, selective degradation, NMR spectroscopy, and electrospray mass spectrometry. The resulting data showed that the parent repeating unit of the exopolysaccharide is a highly branched heptasaccharide with the following structure: Two acetyl groups are present per repeating unit, as noncarbohydrate substituents. Copyright 2000 Academic Press.

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Year:  2000        PMID: 10891376     DOI: 10.1006/bbrc.2000.3059

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN: 0006-291X            Impact factor:   3.575


  18 in total

1.  Functional analysis of Burkholderia cepacia genes bceD and bceF, encoding a phosphotyrosine phosphatase and a tyrosine autokinase, respectively: role in exopolysaccharide biosynthesis and biofilm formation.

Authors:  Ana S Ferreira; Jorge H Leitão; Sílvia A Sousa; Ana M Cosme; Isabel Sá-Correia; Leonilde M Moreira
Journal:  Appl Environ Microbiol       Date:  2006-11-17       Impact factor: 4.792

2.  Cloning, expression, purification, crystallization and preliminary crystallographic studies of BceC, a UDP-glucose dehydrogenase from Burkholderia cepacia IST408.

Authors:  Joana Rocha; Alma O Popescu; Isabel Sá-Correia; Arsénio M Fialho; Carlos Frazão
Journal:  Acta Crystallogr Sect F Struct Biol Cryst Commun       Date:  2010-02-24

3.  σ54-Dependent Response to Nitrogen Limitation and Virulence in Burkholderia cenocepacia Strain H111.

Authors:  Martina Lardi; Claudio Aguilar; Alessandro Pedrioli; Ulrich Omasits; Angela Suppiger; Gerardo Cárcamo-Oyarce; Nadine Schmid; Christian H Ahrens; Leo Eberl; Gabriella Pessi
Journal:  Appl Environ Microbiol       Date:  2015-04-03       Impact factor: 4.792

4.  Functional and topological analysis of the Burkholderia cenocepacia priming glucosyltransferase BceB, involved in the biosynthesis of the cepacian exopolysaccharide.

Authors:  Paula A Videira; Abbner P Garcia; Isabel Sá-Correia
Journal:  J Bacteriol       Date:  2005-07       Impact factor: 3.490

5.  The OmpR Regulator of Burkholderia multivorans Controls Mucoid-to-Nonmucoid Transition and Other Cell Envelope Properties Associated with Persistence in the Cystic Fibrosis Lung.

Authors:  Inês N Silva; Filipa D Pessoa; Marcelo J Ramires; Mário R Santos; Jörg D Becker; Vaughn S Cooper; Leonilde M Moreira
Journal:  J Bacteriol       Date:  2018-08-10       Impact factor: 3.490

6.  Fluorescence and NMR spectroscopy together with molecular simulations reveal amphiphilic characteristics of a Burkholderia biofilm exopolysaccharide.

Authors:  Michelle M Kuttel; Paola Cescutti; Marco Distefano; Roberto Rizzo
Journal:  J Biol Chem       Date:  2017-05-03       Impact factor: 5.157

7.  Studies on the involvement of the exopolysaccharide produced by cystic fibrosis-associated isolates of the Burkholderia cepacia complex in biofilm formation and in persistence of respiratory infections.

Authors:  Mónica V Cunha; Sílvia A Sousa; Jorge H Leitão; Leonilde M Moreira; Paula A Videira; Isabel Sá-Correia
Journal:  J Clin Microbiol       Date:  2004-07       Impact factor: 5.948

8.  Distribution of cepacian biosynthesis genes among environmental and clinical Burkholderia strains and role of cepacian exopolysaccharide in resistance to stress conditions.

Authors:  Ana S Ferreira; Jorge H Leitão; Inês N Silva; Pedro F Pinheiro; Sílvia A Sousa; Christian G Ramos; Leonilde M Moreira
Journal:  Appl Environ Microbiol       Date:  2009-11-30       Impact factor: 4.792

9.  Colonial morphology of Burkholderia cepacia complex genomovar III: implications in exopolysaccharide production, pilus expression, and persistence in the mouse.

Authors:  Jacqueline W Chung; Eleonora Altman; Terry J Beveridge; David P Speert
Journal:  Infect Immun       Date:  2003-02       Impact factor: 3.441

10.  Molecular analysis of Burkholderia cepacia complex isolates from a Portuguese cystic fibrosis center: a 7-year study.

Authors:  Mónica V Cunha; Jorge H Leitão; Eshwar Mahenthiralingam; Peter Vandamme; Luís Lito; Celeste Barreto; Maria José Salgado; Isabel Sá-Correia
Journal:  J Clin Microbiol       Date:  2003-09       Impact factor: 5.948

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