Literature DB >> 10891251

A "traceless" Staudinger ligation for the chemoselective synthesis of amide bonds.

E Saxon1, J I Armstrong, C R Bertozzi.   

Abstract

[reaction: see text] Here we report a novel modification of our previously reported "Staudinger ligation" that generates an amide bond from an azide and a specifically functionalized phosphine. This method for the selective formation of an amide bond, which does not require the orthogonal protection of distal functional groups, should find general utility in synthetic and biological chemistry.

Entities:  

Mesh：

Substances：

Year:  2000        PMID： 10891251     DOI： 10.1021/ol006054v

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  87 in total

1.  Total synthesis of cytochrome b562 by native chemical ligation using a removable auxiliary.

Authors:  D W Low; M G Hill; M R Carrasco; S B Kent; P Botti
Journal:  Proc Natl Acad Sci U S A       Date:  2001-06-05       Impact factor: 11.205

Review 2.  Chemical synthesis of circular proteins.

Authors:  James P Tam; Clarence T T Wong
Journal:  J Biol Chem       Date:  2012-06-14       Impact factor: 5.157

3.  Metabolic Incorporation of N-Acetyl Muramic Acid Probes into Bacterial Peptidoglycan.

Authors:  Kristen E DeMeester; Hai Liang; Junhui Zhou; Kimberly A Wodzanowski; Benjamin L Prather; Cintia C Santiago; Catherine L Grimes
Journal:  Curr Protoc Chem Biol       Date:  2019-12

Review 4.  Bioorthogonal chemistry: recent progress and future directions.

Authors:  Reyna K V Lim; Qing Lin
Journal:  Chem Commun (Camb)       Date:  2010-01-21       Impact factor: 6.222

5.  AMIDE FORMATION BY DECARBOXYLATIVE CONDENSATION OF HYDROXYLAMINES AND α-KETOACIDS: N-[(1S)-1 PHENYLETHYL]-BENZENEACETAMIDE.

Authors:  Lei Ju; Jeffrey W Bode; Tatsuya Toma; Tohru Fukuyama
Journal:  Organic Synth       Date:  2010-12-01

6.  His6 tag-assisted chemical protein synthesis.

Authors:  Duhee Bang; Stephen B H Kent
Journal:  Proc Natl Acad Sci U S A       Date:  2005-03-22       Impact factor: 11.205

7.  Direct screening of solution phase combinatorial libraries encoded with externally sensitized photolabile tags.

Authors:  Rudresha Kottani; Roman A Valiulin; Andrei G Kutateladze
Journal:  Proc Natl Acad Sci U S A       Date:  2006-09-06       Impact factor: 11.205

8.  Design and synthesis of a new steroid-macrocyclic derivative with biological activity.

Authors:  Maria López-Ramos; Lauro Figueroa-Valverde; Socorro Herrera-Meza; Marcela Rosas-Nexticapa; Francisco Díaz-Cedillo; Elodia García-Cervera; Eduardo Pool-Gómez; Regina Cahuich-Carrillo
Journal:  J Chem Biol       Date:  2017-02-23

9.  Tyrosine-sulfate isosteres of CCR5 N-terminus as tools for studying HIV-1 entry.

Authors:  Son N Lam; Priyamvada Acharya; Richard Wyatt; Peter D Kwong; Carole A Bewley
Journal:  Bioorg Med Chem       Date:  2008-10-05       Impact factor: 3.641

10.  A biologically active surface enzyme assembly that attenuates thrombus formation.

Authors:  Zheng Qu; Sharmila Muthukrishnan; Murali K Urlam; Carolyn A Haller; Sumanas W Jordan; Vivek A Kumar; Ulla M Marzec; Yaseen Elkasabi; Joerg Lahann; Stephen R Hanson; Elliot L Chaikof
Journal:  Adv Funct Mater       Date:  2011-09-26       Impact factor: 18.808
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.