Literature DB >> 10890161

Synthesis and uptake of nitric oxide-releasing drugs by the P2 nucleoside transporter in Trypanosoma equiperdum.

L Soulère1, P Hoffmann, F Bringaud, J Périé.   

Abstract

A series of S-nitrosothiols, structurally related to the NO*-donor S-nitroso-N-acetylpenicillamine, and of organic nitrate esters that contain amidine groups which specify a recognition via the trypanosomal purine transporter P2, were synthesized and tested for their ability to inhibit the uptake of [2-(3)H]adenosine on Trypanosoma equiperdum.

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Year:  2000        PMID: 10890161     DOI: 10.1016/s0960-894x(00)00233-x

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN: 0960-894X            Impact factor:   2.823


  1 in total

1.  Quinone-amino acid conjugates targeting Leishmania amino acid transporters.

Authors:  Federica Prati; Adele Goldman-Pinkovich; Federica Lizzi; Federica Belluti; Roni Koren; Dan Zilberstein; Maria Laura Bolognesi
Journal:  PLoS One       Date:  2014-09-25       Impact factor: 3.240

  1 in total

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