Literature DB >> 10890158

A model for ZnII-containing-beta-lactamase: synthesis, X-ray crystal structure of a zinc(II) complex bearing thiol group and hydrolysis of phosphate diester.

H Kurosaki1, T Tawada, S Kawasoe, Y Ohashi, M Goto.   

Abstract

A novel N3S1 typed tripodal ligand bearing an SH group, N-(mercaptoethyl)-di(2-pyridylmethyl)amine, DPASH, was prepared and its zinc(II) complex, [ZnII(DPAS)Cl], was structurally characterized by X-ray crystallography. [ZnII(DPAS)Cl] promoted hydrolysis of sodium bis(p-nitrophenyl)hydrogenphosphate), BNP-.

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Year:  2000        PMID： 10890158     DOI： 10.1016/s0960-894x(00)00238-9

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN： 0960-894X            Impact factor:   2.823


  2 in total

1.  A Cephalosporin-Tripodalamine Conjugate Inhibits Metallo-β-Lactamase with High Efficacy and Low Toxicity.

Authors:  Hongyan Tian; Yiwan Wang; Yang Dai; Anwen Mao; Wanqing Zhou; Xiaoli Cao; Hui Deng; Hao Lu; Lin Ding; Han Shen; Xiaojian Wang
Journal:  Antimicrob Agents Chemother       Date:  2022-09-12       Impact factor: 5.938

2.  In vivo folding of recombinant metallo-beta-lactamase L1 requires the presence of Zn(II).

Authors:  Gopalraj Periyannan; Patrick J Shaw; Tara Sigdel; Michael W Crowder
Journal:  Protein Sci       Date:  2004-07-06       Impact factor: 6.725
  2 in total

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