Literature DB >> 10889061

Notch signal transduction: a real rip and more.

G Weinmaster1.   

Abstract

The Notch signaling pathway functions in a wide variety of processes that regulate tissue patterning and morphogenesis in developing vertebrates and invertebrates. Research on the mechanism of ligand-induced Notch signal transduction has revealed a novel and essential element in the signal cascade. Some recent findings support a model in which sequential proteolytic cleavage serves to regulate Notch signal transduction.

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Year:  2000        PMID： 10889061     DOI： 10.1016/s0959-437x(00)00097-6

Source DB:  PubMed          Journal:  Curr Opin Genet Dev        ISSN： 0959-437X            Impact factor:   5.578


  66 in total

1.  Presenilin-dependent gamma-secretase activity modulates thymocyte development.

Authors:  P Doerfler; M S Shearman; R M Perlmutter
Journal:  Proc Natl Acad Sci U S A       Date:  2001-07-24       Impact factor: 11.205

2.  Nuclear localization of CBF1 is regulated by interactions with the SMRT corepressor complex.

Authors:  S Zhou; S D Hayward
Journal:  Mol Cell Biol       Date:  2001-09       Impact factor: 4.272

3.  CADASIL Notch3 mutant proteins localize to the cell surface and bind ligand.

Authors:  Talin Haritunians; Jim Boulter; Carol Hicks; Jonathon Buhrman; Guy DiSibio; Carrie Shawber; Gerry Weinmaster; Donna Nofziger; Carolyn Schanen
Journal:  Circ Res       Date:  2002-03-22       Impact factor: 17.367

4.  Nrarp is a novel intracellular component of the Notch signaling pathway.

Authors:  E Lamar; G Deblandre; D Wettstein; V Gawantka; N Pollet; C Niehrs; C Kintner
Journal:  Genes Dev       Date:  2001-08-01       Impact factor: 11.361

5.  Members of the Jagged/Notch gene families are expressed in injured arteries and regulate cell phenotype via alterations in cell matrix and cell-cell interaction.

Authors:  V Lindner; C Booth; I Prudovsky; D Small; T Maciag; L Liaw
Journal:  Am J Pathol       Date:  2001-09       Impact factor: 4.307

6.  The lytic switch protein of KSHV activates gene expression via functional interaction with RBP-Jkappa (CSL), the target of the Notch signaling pathway.

Authors:  Yuying Liang; Jean Chang; Stephen J Lynch; David M Lukac; Don Ganem
Journal:  Genes Dev       Date:  2002-08-01       Impact factor: 11.361

7.  Alagille syndrome and Wilson disease in siblings: a diagnostic conundrum.

Authors:  Meghan Amson; Esther Lamoureux; Nir Hilzenrat; Marc Tischkowitz
Journal:  Can J Gastroenterol       Date:  2012-06       Impact factor: 3.522

8.  Notch signaling and neurogenesis in normal and stroke brain.

Authors:  Mei-Juan Xiao; Zhao Han; Bei Shao; Kunlin Jin
Journal:  Int J Physiol Pathophysiol Pharmacol       Date:  2009-11-10

9.  The RNA-binding protein Musashi-1 regulates proteasome subunit expression in breast cancer- and glioma-initiating cells.

Authors:  Chann Lagadec; Erina Vlashi; Patricia Frohnen; Yazeed Alhiyari; Mabel Chan; Frank Pajonk
Journal:  Stem Cells       Date:  2014-01       Impact factor: 6.277

10.  Fringe glycosyltransferases differentially modulate Notch1 proteolysis induced by Delta1 and Jagged1.

Authors:  Liang-Tung Yang; James T Nichols; Christine Yao; Jennifer O Manilay; Ellen A Robey; Gerry Weinmaster
Journal:  Mol Biol Cell       Date:  2004-12-01       Impact factor: 4.138
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