| Literature DB >> 10888323 |
K J Shin1, K D Koo, K H Yoo, D C Kim, D J Kim, S W Park.
Abstract
The synthesis and biological activities of a series of new 1beta-methylcarbapenems 1a-l having tetrazolothioether moiety at C-5 position of pyrrolidine were described. Among these compounds, 1c showed the most potent antibacterial activity and advanced pharmacokinetics compared with imipenem and meropenem.Entities:
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Year: 2000 PMID： 10888323 DOI： 10.1016/s0960-894x(00)00253-5
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823