Literature DB >> 10886608

Susceptibility of multiresistant strains of Burkholderia cepacia to honey.

R A Cooper1, P Wigley, N F Burton.   

Abstract

Twenty strains of Burkholderia cepacia, isolated principally from the sputum of cystic fibrosis patients, were tested for their susceptibility to eight antibiotics with a modified Kirby-Bauer Disc diffusion technique. All strains exhibited multiple but not identical patterns of antibiotic resistance. The sensitivity of all strains to honey was assessed with an agar dilution method. All strains exhibited susceptibility to concentrations of honey below 6% (v/v). This suggests that honey may have a potential role in the clinical management of B. cepacia infections.

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Year:  2000        PMID: 10886608     DOI: 10.1046/j.1472-765x.2000.00756.x

Source DB:  PubMed          Journal:  Lett Appl Microbiol        ISSN: 0266-8254            Impact factor:   2.858


  8 in total

1.  The unusual antibacterial activity of medical-grade Leptospermum honey: antibacterial spectrum, resistance and transcriptome analysis.

Authors:  S E Blair; N N Cokcetin; E J Harry; D A Carter
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2009-06-10       Impact factor: 3.267

2.  Medical-grade honey enriched with antimicrobial peptides has enhanced activity against antibiotic-resistant pathogens.

Authors:  P H S Kwakman; L de Boer; C P Ruyter-Spira; T Creemers-Molenaar; J P F G Helsper; C M J E Vandenbroucke-Grauls; S A J Zaat; A A te Velde
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2010-10-07       Impact factor: 3.267

3.  The antibacterial activity of honey derived from Australian flora.

Authors:  Julie Irish; Shona Blair; Dee A Carter
Journal:  PLoS One       Date:  2011-03-28       Impact factor: 3.240

4.  Mechanism of Honey Bacteriostatic Action Against MRSA and VRE Involves Hydroxyl Radicals Generated from Honey's Hydrogen Peroxide.

Authors:  Katrina Brudzynski; Robert Lannigan
Journal:  Front Microbiol       Date:  2012-02-07       Impact factor: 5.640

5.  Powerful bacterial killing by buckwheat honeys is concentration-dependent, involves complete DNA degradation and requires hydrogen peroxide.

Authors:  Katrina Brudzynski; Kamal Abubaker; Tony Wang
Journal:  Front Microbiol       Date:  2012-07-04       Impact factor: 5.640

6.  A demonstration of the susceptibility of clinical isolates obtained from cystic fibrosis patients to manuka honey.

Authors:  Rowena Jenkins; Mandy Wootton; Robin Howe; Rose Cooper
Journal:  Arch Microbiol       Date:  2015-02-14       Impact factor: 2.552

7.  Antibacterial compounds of Canadian honeys target bacterial cell wall inducing phenotype changes, growth inhibition and cell lysis that resemble action of β-lactam antibiotics.

Authors:  Katrina Brudzynski; Calvin Sjaarda
Journal:  PLoS One       Date:  2014-09-05       Impact factor: 3.240

Review 8.  Therapeutic Manuka Honey: No Longer So Alternative.

Authors:  Dee A Carter; Shona E Blair; Nural N Cokcetin; Daniel Bouzo; Peter Brooks; Ralf Schothauer; Elizabeth J Harry
Journal:  Front Microbiol       Date:  2016-04-20       Impact factor: 5.640

  8 in total

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