Literature DB >> 10885358

Reduction in incidence of severe paracetamol poisoning.

M I Prince, S H Thomas, O F James, M Hudson.   

Abstract

We report substantial reductions in the frequency of severe paracetamol hepatotoxicity locally and nationally after legislative limitations on its sale. These reductions were not explained by changes in referral patterns or use of N-acetylcysteine.

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Year:  2000        PMID： 10885358     DOI： 10.1016/S0140-6736(00)02354-0

Source DB:  PubMed          Journal:  Lancet        ISSN： 0140-6736            Impact factor:   79.321


  15 in total

1.  Severity of overdose after restriction of paracetamol availability. Study's results conflict with those of other papers.

Authors:  C L Sheen; T M MacDonald
Journal:  BMJ       Date:  2001-03-03

2.  Severity of overdose after restriction of paracetamol availability: retrospective study.

Authors:  D Robinson; A M Smith; G D Johnston
Journal:  BMJ       Date:  2000-10-14

3.  Effects of legislation restricting pack sizes of paracetamol and salicylate on self poisoning in the United Kingdom: before and after study.

Authors:  K Hawton; E Townsend; J Deeks; L Appleby; D Gunnell; O Bennewith; J Cooper
Journal:  BMJ       Date:  2001-05-19

4.  The epidemiology of self-poisoning in the UK.

Authors:  D R Camidge; R J Wood; D N Bateman
Journal:  Br J Clin Pharmacol       Date:  2003-12       Impact factor: 4.335

5.  Legislation restricting paracetamol sales and patterns of self-harm and death from paracetamol-containing preparations in Scotland.

Authors:  D N Bateman; D R Gorman; M Bain; J H C Inglis; F R House; D Murphy
Journal:  Br J Clin Pharmacol       Date:  2006-11       Impact factor: 4.335

6.  Ease of access is a principal factor in the frequency of paracetamol overdose.

Authors:  M O'Rourke; M R Garland; P A McCormick
Journal:  Ir J Med Sci       Date:  2002 Jul-Sep       Impact factor: 1.568

7.  UK legislation on analgesic packs: before and after study of long term effect on poisonings.

Authors:  Keith Hawton; Sue Simkin; Jonathan Deeks; Jayne Cooper; Amy Johnston; Keith Waters; Morag Arundel; William Bernal; Bridget Gunson; Mark Hudson; Deepak Suri; Kenneth Simpson
Journal:  BMJ       Date:  2004-10-29

8.  Detailed analyses of self-poisoning episodes presenting to a large regional teaching hospital in the UK.

Authors:  Katherine Prescott; Richard Stratton; Anette Freyer; Ian Hall; Ivan Le Jeune
Journal:  Br J Clin Pharmacol       Date:  2009-08       Impact factor: 4.335

Review 9.  Impact of restricting paracetamol pack sizes on paracetamol poisoning in the United Kingdom: a review of the literature.

Authors:  Leonard C Hawkins; John N Edwards; Paul I Dargan
Journal:  Drug Saf       Date:  2007       Impact factor: 5.606

10.  Paracetamol-related deaths in Scotland, 1994-2000.

Authors:  Christopher L Sheen; John F Dillon; D Nicholas Bateman; Kenneth J Simpson; Thomas M MacDonald
Journal:  Br J Clin Pharmacol       Date:  2002-10       Impact factor: 4.335
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